Document Detail

Coronary flow velocity reserve in patients with ischemic stroke.
MedLine Citation:
PMID:  19644413     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The usefulness and safety of coronary flow velocity reserve (CFVR) in patients with acute ischemic stroke were examined. MATERIAL/METHODS: We studied 36 patients with acute ischemic stroke. Transthoracic Doppler recording of diastolic coronary flow velocity was performed at baseline and after maximal vasodilation by adenosine triphosphate infusion. CFVR was defined as the ratio of hyperemic to basal averaged peak coronary flow velocity. Patients with CFVR <2.1 were assigned in Positive group. RESULTS: Fourteen patients had impaired CFVR. Age over 70 years and arterial stenosis were more frequent in the Positive group. In the Positive group, 11 underwent coronary angiography; 9 of them had some abnormal findings. The positive predictive value of impaired CFVR for detecting coronary artery disease was 82%. CONCLUSIONS: CFVR is useful for detecting coronary heart disease in stroke patients, and may be indicated in patients over 70 years or in those with arterial stenosis.
Makoto Nakajima; Hideki Doi; Teruyuki Hirano; Makoto Uchino
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medical science monitor : international medical journal of experimental and clinical research     Volume:  15     ISSN:  1643-3750     ISO Abbreviation:  Med. Sci. Monit.     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-07-31     Completed Date:  2009-10-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9609063     Medline TA:  Med Sci Monit     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  CR383-8     Citation Subset:  IM    
Department of Medicine, Kumamoto Rosai Hospital, Yatsushiro, Japan.
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MeSH Terms
Blood Flow Velocity / physiology*
Coronary Circulation / physiology*
Coronary Disease / complications,  diagnosis,  physiopathology
Fractional Flow Reserve, Myocardial / physiology
Myocardial Ischemia / complications*,  physiopathology*
Stroke / complications*,  physiopathology*

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