Document Detail

Coronary flow velocity reserve is diminished in hypertensive left ventricular hypertrophy.
MedLine Citation:
PMID:  15815773     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Dipyridamole stress transesophageal echocardiography (STEE) is a feasible method for the evaluation of coronary flow velocity reserve (CFR). AIM: The aim of the present study was to investigate CFR in hypertensive patients with or without left ventricular hypertrophy (LVH). METHODS: The study comprised 73 patients with a negative coronary angiogram (29 men and 44 women). Three different groups were compared: normotensive patients, hypertensive patients without LVH and hypertensive patients with LVH. RESULTS: CFR was significantly decreased in patients with hypertension with LVH as compared to normotensive cases (2.19+/-0.50 vs 2.71+/-1.10; p<0.05). CFR of hypertensive patients without LVH was only slightly reduced as compared to normotensive cases (2.44+/-0.81 vs 2.71+/-1.10; p=ns). In hypertensive patients with LVH, the LV mass and LV mass index were inversely related to CFR (r = -0.481 and -0.477, p<0.05, respectively). CONCLUSIONS: CFR is diminished in patients with hypertension. The degree of CFR reduction is related to the extent of LVH.
Attila Nemes; Klara Neu; Tamas Forster; Zsolt Kovacs; Miklos Csanady
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Kardiologia polska     Volume:  62     ISSN:  0022-9032     ISO Abbreviation:  Kardiol Pol     Publication Date:  2005 Jan 
Date Detail:
Created Date:  2005-04-07     Completed Date:  2005-06-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376352     Medline TA:  Kardiol Pol     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  1-5     Citation Subset:  IM    
2nd Department of Medicine and Cardiology Centre, University of Szeged, Hungary.
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MeSH Terms
Blood Flow Velocity
Case-Control Studies
Coronary Circulation*
Coronary Vessels / drug effects
Dipyridamole / pharmacology
Echocardiography, Stress
Echocardiography, Transesophageal
Hypertension / complications*,  physiopathology*
Hypertrophy, Left Ventricular / etiology*,  physiopathology*
Middle Aged
Vasodilator Agents / pharmacology
Reg. No./Substance:
0/Vasodilator Agents; 58-32-2/Dipyridamole

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