Document Detail


Coronary dual source multi detector computed tomography in patients suspected of coronary artery disease: Prevalence of incidental extra-cardiac findings.
MedLine Citation:
PMID:  20674205     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
OBJECTIVES: (1) To establish the prevalence of incidental extra-cardiac findings (ECFs) in coronary multi detector computed tomography (CCT) performed in a large, homogeneous cohort of patients suspected of coronary artery disease (CAD). (2) To examine whether any association can be established between ECFs and pretest risk as determined by conventional risk factors for CAD, the Diamond-Forrester risk model or coronary artery calcium scores. (3) To assess cost related to extra-cardiac examinations.
DESIGN: Retrospective study of consecutive patients who had CCT performed. A large field of view was recreated from the non-enhanced CT scan and evaluated by a radiologist for incidental ECFs.
SUBJECTS: Patients with chest pain referred to CTA by a cardiologist.
RESULTS: In 1383 patients a total of 481 ECFs were indentified, 378 minor (meaning no follow-up was needed) and 103 major ECFs (ECF followed up clinically and/or with additional imaging), in a total of 393 (28%) patients. 85 (6%) patients had one major ECF and 9 (0.7%) patients had two major ECFs. In 19 (4 cases of malignancy) patients the major ECF had therapeutic consequences. Significant positive associations were found between age and smoking, respectively and the presence of ECFs. The cost estimate of saving one life from malignant disease based on ECF examinations is 40,190€.
CONCLUSION: Incidental extra-cardiac findings are common, sometimes revealing serious, even malignant disease. Diagnostic follow-up of major ECFs seems to be cost-effective in a Danish clinical setting. We recommend investigating a large field of view for incidental ECFs following CCT.
Authors:
K Bendix; J M Jensen; S Poulsen; N Mygind; B L Nørgaard
Related Documents :
7707625 - Variation in patient utilities for outcomes of the management of chronic stable angina....
16494885 - Cd40-cd154 expression in calcified and non-calcified coronary lesions of patients with ...
2912435 - Progression of coronary atherosclerosis in patients with probable familial hypercholest...
8432125 - Early and late exercise testing. usefulness after percutaneous transluminal coronary an...
7235905 - Behavioral approaches to treatment of chronic pain: the inaccuracy of patient self-repo...
12627855 - Clinical significance of fragmented red cells after allogeneic bone marrow transplantat...
Publication Detail:
Type:  Journal Article     Date:  2010-07-31
Journal Detail:
Title:  European journal of radiology     Volume:  80     ISSN:  1872-7727     ISO Abbreviation:  Eur J Radiol     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-09-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8106411     Medline TA:  Eur J Radiol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  109-14     Citation Subset:  IM    
Copyright Information:
Copyright © 2010. Published by Elsevier Ireland Ltd.
Affiliation:
Department of Cardiology, Vejle Hospital, Vejle, Denmark.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  High-resolution phase-contrast MRI of aortic and pulmonary blood flow during rest and physical exerc...
Next Document:  Focal ground-glass opacities in non-small cell lung carcinoma resection patients.