Document Detail

Coronary computed tomography angiography---a promising imaging modality in diagnosing coronary artery disease.
MedLine Citation:
PMID:  18490228     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Traditionally, information on coronary artery lesions is obtained from invasive coronary angiography (CAG). The clinical applicability and diagnostic performance of the newly developed 64-slice multislice computed tomography (MSCT) scanner in coronary angiographic evaluation is not well evaluated. METHODS: Coronary computed tomography angiography (CCTA) was performed in 345 patients (119 women, 226 men; mean age, 59.64 +/- 11.67 years). Concomitant CAG was performed in 53 patients. The diagnostic performance of CCTA for detecting significant lesions was compared with that of CAG by 3 independent cardiologists. RESULTS: All CCTA was performed without complication. Comparison between CCTA and CAG was made in the 53 patients who underwent both studies. Sensitivity, specificity and the positive and negative predictive values for the 53 patients were: 81%, 99%, 87% and 99%, respectively. CONCLUSION: The 64-slice MSCT, developed in recent years, allows reliable noninvasive evaluation of coronary artery morphology, including plaque, stenosis and congenital anomaly. The diagnostic accuracy of MSCT scans for detecting lesions makes it a good imaging substitute for CAG in the evaluation of these coronary segments.
Shu-Chen Han; Ching-Chang Fang; Yi Chen; Chi-Liang Chen; Shih-Pu Wang
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the Chinese Medical Association : JCMA     Volume:  71     ISSN:  1726-4901     ISO Abbreviation:  J Chin Med Assoc     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-05-20     Completed Date:  2008-08-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101174817     Medline TA:  J Chin Med Assoc     Country:  China (Republic : 1949- )    
Other Details:
Languages:  eng     Pagination:  241-6     Citation Subset:  IM    
Department of Radiology, Tainan Municipal Hospital, Tainan, Taiwan, ROC.
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MeSH Terms
Coronary Angiography / methods*
Coronary Artery Disease / radiography*
Coronary Stenosis / radiography
Coronary Vessel Anomalies / radiography
Middle Aged
Sensitivity and Specificity
Tomography, X-Ray Computed / methods*
Comment In:
J Chin Med Assoc. 2008 May;71(5):232-3   [PMID:  18490226 ]

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