| Coronary circulation and myocardial metabolism in dilated cardiomyopathy. | |
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MedLine Citation:
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PMID: 3792006 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Chest pain is a frequent complaint in patients with dilated cardiomyopathy (DCMP). Myocardial blood flow, coronary circulation parameters and coronary sinus lactate content were measured in 14 patients with DCMP and 10 healthy subjects. Myocardial blood flow in DCMP was 53.1 +/- 3.3 vs. 66.3 +/- 4.9 ml/min/100 g in the control group (p less than 0.05), coronary driving pressure was 59.1 +/- 4.6 vs. 72.8 +/- 8.8 mmHg (p less than 0.01). Subendocardial flow index (DPTI/TTI) in DCMP was 0.76 +/- 0.12 vs. 1.15 +/- 0.19 (p less than 0.01). The lactate content in coronary sinus blood was greater (1.93 +/- 0.45 mmol/l) than in the control group (1.43 +/- 0.48) (p less than 0.05). These results suggest that in DCMP myocardial blood flow is decreased, and in the majority of patients lactate is produced. Thus, it is possible that pain in DCMP is of anginal origin. |
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Authors:
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J S Dubiel; J P Dubiel; J Frendo; K Zmudka; T Horzela |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Cor et vasa Volume: 28 ISSN: 0010-8650 ISO Abbreviation: Cor Vasa Publication Date: 1986 |
Date Detail:
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Created Date: 1987-02-17 Completed Date: 1987-02-17 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0372614 Medline TA: Cor Vasa Country: CZECHOSLOVAKIA |
Other Details:
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Languages: eng Pagination: 356-64 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Cardiomyopathy, Dilated / blood, physiopathology* Coronary Circulation* Female Hemodynamics Humans Lactates / blood Male Middle Aged Myocardium / metabolism* Oxygen / blood |
| Chemical | |
Reg. No./Substance:
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0/Lactates; 7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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