| Coronary calcification in patients with marker-positive acute coronary syndrome. | |
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MedLine Citation:
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PMID: 20849316 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The value of assessing coronary artery calcium (CAC) with regard to characterizing unstable coronary artery disease remains controversial. PURPOSE: To evaluate the amount of CAC in patients with an acute marker-positive coronary syndrome in segments containing the culprit lesion compared with the remote coronary segments. MATERIAL AND METHODS: Thirty-two patients with a marker-positive acute coronary syndrome were examined using electron-beam computed tomography (EBCT), selective coronary angiography and, in some, intravascular ultrasound. The coronary anatomy was analyzed according to the segmental classification proposed by the American Heart Association (AHA). RESULTS: The total EBCT coronary artery calcium score (CAC, Agatston method) was 251±371 (range 0-1629). In 81% of the patients, a greater CAC score was observed than expected on the basis of age and gender. In 30 patients, significant stenoses were detected. The CAC score of the culprit vessel was 108±163 vs 78±134 in the non-culprit vessels and did not differ significantly (P=0.4). The mean CAC score of the coronary segment (AHA classification) containing the culprit lesion was 51±82 vs 29±45 in the other coronary artery segments (P=0.14). Of the two patients with no CAC detected by EBCT, one had no coronary atherosclerosis (confirmed by intravascular ultrasound) and one had one vessel coronary artery disease. CONCLUSION: Coronary calcium related to the culprit lesion in patients with a marker-positive acute coronary syndrome showed a tendency for an increased amount but was not statistically different from the amount of coronary calcium in remote vessel segments. |
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Authors:
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Thomas Voigtländer; Stefan Möhlenkamp; Holger Eggebrecht; Thomas Budde; Raimund Erbel; Axel Schmermund |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta radiologica (Stockholm, Sweden : 1987) Volume: 51 ISSN: 1600-0455 ISO Abbreviation: Acta Radiol Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-10-14 Completed Date: 2010-11-26 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8706123 Medline TA: Acta Radiol Country: England |
Other Details:
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Languages: eng Pagination: 977-81 Citation Subset: IM |
Affiliation:
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Cardioangiologic Center Bethanien (CCB), Frankfurt/M, Germany. t.voigtlaender@ccb.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Coronary Syndrome
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radiography*,
therapy,
ultrasonography Adult Aged Analysis of Variance Angioplasty, Balloon Calcinosis / radiography*, ultrasonography Coronary Angiography Female Humans Male Middle Aged Thrombolytic Therapy Tomography, X-Ray Computed / methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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