| Coronary blood flow and lactate metabolism during isometric handgrip exercise in heart disease. | |
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MedLine Citation:
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PMID: 1011367 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Twenty-one patients with various heart diseases undergoing the coronary sinus catheterization had myocardial blood flow studies before and during isometric handgrip exercise. At 30% of the maximal voluntary contraction (MVC), handgrip increased both coronary sinus blood flow by 19.8% and myocardial O2 consumption by 21.0% on the average as compared to those at rest. At 20% of MVC, the increase of the both was slight except for 1 case. The increase in coronary sinus blood flow significantly correlated to the increase of myocardial O2 consumption. Lactate extraction ratio decreased to less than 10% during handgrip in 4 of 19 cases studied despite of normal values at rest. Lactate extraction ratio had significantly positive correlations with coronary sinus blood flow and myocardial O2 consumption during handgrip, while there were not significant ones at rest. It is suggested that isometric handgrip exercise is useful as a stress test for detection of myocardial ischemia in the heart of coronary artery disease. |
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Authors:
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R Katori; K Miyazawa; S Ikeda; K Shirato; I Muraguchi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Japanese heart journal Volume: 17 ISSN: 0021-4868 ISO Abbreviation: Jpn Heart J Publication Date: 1976 Nov |
Date Detail:
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Created Date: 1977-03-31 Completed Date: 1977-03-31 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0401175 Medline TA: Jpn Heart J Country: JAPAN |
Other Details:
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Languages: eng Pagination: 742-52 Citation Subset: IM; S |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Coronary Circulation* Coronary Disease / metabolism* Female Hand / physiology Humans Lactates / metabolism* Male Middle Aged Muscle Contraction Myocardium / metabolism Oxygen Consumption Physical Exertion* |
| Chemical | |
Reg. No./Substance:
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0/Lactates |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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