Document Detail


Coronary artery vasomotion after percutaneous transluminal coronary angioplasty.
MedLine Citation:
PMID:  9383584     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Substantial evidence of postangioplasty vasoconstriction is available, both at the dilated site and distal to balloon injury, demonstrating its frequent occurrence. It is likely that even mild or moderate vasoconstriction at the site of balloon injury may create flow turbulence, promoting platelet aggregation and contributing to thrombotic vessel closure. The regulation of arterial smooth muscle tone is a complex process and should be distinguished from elastic recoil, which occurs at the site of balloon injury due to passive elastic properties of the artery, generally immediately after balloon deflation. The contribution of a variety of messengers generated by humoral, neurogenic, myogenic, and endothelium-derived factors in this regulatory process has been implicated. The possible mechanisms of post-percutaneous transluminal coronary angioplasty vasoconstriction at the dilated site (local) and in segments of coronary artery beyond the dilated site (distal) are reviewed in this article.
Authors:
V K Misra; M Agirbasli; T A Fischell
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinical cardiology     Volume:  20     ISSN:  0160-9289     ISO Abbreviation:  Clin Cardiol     Publication Date:  1997 Nov 
Date Detail:
Created Date:  1997-12-18     Completed Date:  1997-12-18     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7903272     Medline TA:  Clin Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  915-22     Citation Subset:  IM    
Affiliation:
Division of Cardiology/Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
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MeSH Terms
Descriptor/Qualifier:
Angioplasty, Transluminal, Percutaneous Coronary*
Animals
Constriction, Pathologic
Coronary Disease / pathology,  physiopathology,  therapy*
Coronary Vessels / pathology,  physiology*
Endothelium, Vascular / physiology
Homeostasis
Humans
Nitric Oxide / physiology
Vasoconstriction*
Chemical
Reg. No./Substance:
10102-43-9/Nitric Oxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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