Document Detail

Coronary artery spasm and ventricular arrhythmias.
MedLine Citation:
PMID:  22438089     Owner:  NLM     Status:  Publisher    
Coronary artery spasm (CAS) is characterised by chest pain at rest and transient ST segment elevation on the ECG. The natural history of variant angina is not fully understood. Patients with CAS are younger, mostly female subjects and usually do not have traditional cardiovascular risk factors other than cigarette smoking. Cardiac arrhythmias are known to be associated with CAS. Ventricular arrhythmia is a well-recognised complication and sudden cardiac death has also been documented. The most important diagnostic tool in CAS is coronary angiography. 24 h ECG Holter monitoring can be very useful in the diagnosis of ventricular arrhythmias caused by CAS. The mainstay therapy for CAS is calcium channel blockers and nitrates. The use of β-blockers, especially the non-selective group, can promote attacks or prolong vasospastic state. The indication for implantable cardioverter defibrillator (ICD) implantation in a patient with CAS is still not clearly established. The role of primary prevention with the use of ICD is controversial; however, ICD implantation should be considered in high risk patients despite optimal medical treatment.
Khang Li Looi; Andrew Grace; Sharad Agarwal
Related Documents :
12459039 - Validation of heart failure events in the antihypertensive and lipid lowering treatment...
20819619 - Prognostic value of baseline c-reactive protein levels in patients undergoing coronary ...
19064009 - Influence of socioeconomic status on lifestyle behavior modifications among survivors o...
8174589 - Clinical results of coronary excimer laser angioplasty: report from the european corona...
19821319 - Alpha-2 adrenergic agonists for the prevention of cardiac complications among patients ...
17975119 - Association of gene variants with incident myocardial infarction in the cardiovascular ...
2773789 - A simplified approach for evaluating multiple test outcomes and multiple disease states...
9794359 - Late coronary angioplasty and ventricular late potentials.
2410739 - Arachidonic acid cascade and the generation of ischemia- and reperfusion-induced ventri...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-3-21
Journal Detail:
Title:  Postgraduate medical journal     Volume:  -     ISSN:  1469-0756     ISO Abbreviation:  -     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-3-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0234135     Medline TA:  Postgrad Med J     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Cardiology, Papworth Hospital NHS Foundation Trust, Cambridge, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Successful retrograde arterial inflow through a muscular branch in a free anterolateral thigh chimer...
Next Document:  Cooperate concept of metastasis: site-specific requirement of activated differentiation and dynamic ...