Document Detail

Coronary artery plaque rapidly induced by local electromagnetic stimulation in the baboon.
MedLine Citation:
PMID:  2767087     Owner:  NLM     Status:  MEDLINE    
A reliable method has been developed to produce stenosis of the right coronary artery of baboons as a consequence of electrostimulation of the vessel at a chosen position. At that site a pair of electrodes were implanted and activated with a train of 9-volt pulses (length: 10 ms, separation: 100 ms) for 30 min, 5 days/week, up to 6 weeks. 13 animals were included in the experiment, 2 of those served as controls. Pathohistologically the structure of the artificially produced constrictions is similar to atherosclerotic lesions. On average the stenoses occupied 55% of the available lumen; total occlusion and no stenosis were observed in 1 case each.
H Breuer; J Fincham; P Hinrichsen; C J Uys; H Weich; B Reichart
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes     Volume:  21     ISSN:  0014-312X     ISO Abbreviation:  Eur Surg Res     Publication Date:  1989  
Date Detail:
Created Date:  1989-10-03     Completed Date:  1989-10-03     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0174752     Medline TA:  Eur Surg Res     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  123-8     Citation Subset:  IM    
Department of Cardiothoracic Surgery, University of Cape Town, South Africa.
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MeSH Terms
Coronary Disease / etiology*,  pathology
Coronary Vessels / pathology
Diet, Atherogenic
Disease Models, Animal
Electric Stimulation*
Electromagnetic Phenomena

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