| Coronary artery lesions and human immunodeficiency virus infection. | |
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MedLine Citation:
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PMID: 8356344 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The postmortem anatomopathological examination of eight heart-and-lung specimens obtained from eight HIV-seropositive patients was performed. Three patients were CDC stage II and five patients were CDC stage IV. The mean age was 27 (range: 23-32). Distal and proximal vascular lesions of the coronary arteries were observed. These impairments were marked by major excentric atherosclerosis (with 80-90% obstruction of the arterial lumen) or by fibrosis two-fold or six-fold the thickness of the tunica media. Sclero-hyalinosis of the smaller arteries and myocardial interstitial fibrosis lesions was also revealed. In view of the severity of the described lesions, the absence of any associated cardiovascular risk factors and the context of immunodepression, the role of a virus in the genesis of these lesions is suggested, in particular a virus of the herpes group. |
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Authors:
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P Paton; A Tabib; R Loire; R Tete |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Research in virology Volume: 144 ISSN: 0923-2516 ISO Abbreviation: Res. Virol. Publication Date: 1993 May-Jun |
Date Detail:
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Created Date: 1993-09-21 Completed Date: 1993-09-21 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8907469 Medline TA: Res Virol Country: FRANCE |
Other Details:
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Languages: eng Pagination: 225-31 Citation Subset: IM; X |
Affiliation:
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Service de Médecine Interne, Hôpital de l'Hôtel-Dieu, Lyon, France. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Arteriosclerosis / etiology, pathology Coronary Disease / epidemiology, etiology, pathology Coronary Vessels / pathology* HIV Infections / complications, pathology* HIV Seropositivity / pathology Humans Male Retrospective Studies Risk Factors |
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