| Coronary artery intervention after cytostatics treatment in unstable angina patient with essential thrombocythemia. A case report and literature review. | |
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MedLine Citation:
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PMID: 16913448 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Essential thrombocythemia (ET) is a clonal disorder of myeloid stem cells that causes thrombocytosis. As a result, ET can lead to vascular thrombosis and tissue ischemia; the association of coronary artery abnormalities such as myocardial infarction or unstable angina is rare. Here we describe a 45,-year-old male patient with essential thrombocythemia who presented with unstable angina. Elective coronary angiography showed total occlusion of mid right coronary artery and mid left anterior descending coronary artery. ET was confirmed by a bone marrow biopsy; treatment was started with antiplatelet therapy including aspirin and clopidogrel along with cytostatic therapy with hydroxyurea and anagrelide. After the initiation of the treatment, the platelet count decreased to 20 x 10(4)/microL. In addition, percutaneous coronary angioplasty was successfully performed with stent placement at the right coronary artery without hemorrhagic or thrombotic complications. |
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Authors:
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Hyun Chang; Chi Young Shim; June-Won Cheong; Ju-Yeon Pyo; Young Guk Ko; Donghoon Choi; Yangsoo Jang |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The Korean journal of internal medicine Volume: 21 ISSN: 1226-3303 ISO Abbreviation: Korean J. Intern. Med. Publication Date: 2006 Jun |
Date Detail:
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Created Date: 2006-08-17 Completed Date: 2006-09-21 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 8712418 Medline TA: Korean J Intern Med Country: Korea (South) |
Other Details:
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Languages: eng Pagination: 146-9 Citation Subset: IM |
Affiliation:
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Division of Cardiology, Yonsei Cardiovascular Center, Yonsei University College of Medicine, Seoul, Korea. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Angina, Unstable
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etiology,
therapy* Angioplasty, Transluminal, Percutaneous Coronary* Humans Hydroxyurea / therapeutic use Male Middle Aged Quinazolines / therapeutic use Stents* Thrombocythemia, Essential / complications, drug therapy* |
| Chemical | |
Reg. No./Substance:
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0/Quinazolines; 0/anagrelide; 127-07-1/Hydroxyurea |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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