| Coronary artery dynamics in vivo. | |
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MedLine Citation:
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PMID: 12085995 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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There is considerable evidence that the localization and evolution of vascular disease are mediated, at least in part, by mechanical factors. The mechanical environment of the coronary arteries, which are tethered to the beating heart, is influenced by cardiac motion; the motion of the vessels must be described quantitatively to characterize fully the mechanical forces acting on and in the vessel wall. Several techniques that have been used to characterize coronary artery dynamics from biplane cineangiograms are described and illustrated. There is considerable variability in dynamic geometric parameters from site to site along a vessel, between the right and left anterior descending arteries, and among individuals, consistent with the hypotheses that variations in stresses mediated by geometry and dynamics affect the localization of atherosclerosis and individual risk of coronary heart disease. The few frankly atherosclerotic vessels that have been examined exhibit high torsions in the neighborhood of lesions, an observation which may have etiologic or diagnostic implications. |
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Authors:
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Zhaohua Ding; Hui Zhu; Morton H Friedman |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Annals of biomedical engineering Volume: 30 ISSN: 0090-6964 ISO Abbreviation: Ann Biomed Eng Publication Date: 2002 Apr |
Date Detail:
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Created Date: 2002-06-27 Completed Date: 2003-01-08 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0361512 Medline TA: Ann Biomed Eng Country: United States |
Other Details:
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Languages: eng Pagination: 419-29 Citation Subset: IM |
Affiliation:
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Department of Diagnostic Radiology, Yale University, New Haven, CT, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Algorithms Arteries / physiopathology Cineangiography / instrumentation, methods* Coronary Angiography / instrumentation, methods* Coronary Artery Disease / physiopathology*, radiography* Coronary Vessels / physiopathology* Humans Imaging, Three-Dimensional / methods* Motion Phantoms, Imaging Radiographic Image Enhancement / methods Sensitivity and Specificity Torsion Abnormality / physiopathology, radiography |
| Grant Support | |
ID/Acronym/Agency:
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HL58856/HL/NHLBI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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