Document Detail


Coronary artery disease in patients undergoing TAVI: why, what, when and how to treat.
MedLine Citation:
PMID:  25256334     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Coronary artery disease (CAD) and aortic valve stenosis (AS) are frequently coexisting. It has been reported that CAD is present in 40% of patients with AS undergoing surgical aortic valve replacement, and in up to 60% of patients with AS undergoing transcatheter aortic valve implantation (TAVI). Elderly patients with CAD and AS are characterised by higher baseline risk profiles as compared to patients with isolated AS, increasing the complexity of their therapeutic management. In patients with CAD and AS the combination of coronary artery bypass grafting (CABG) and surgical aortic valve replacement has been shown to improve survival. Therefore, CABG is recommended in patients with CAD and AS undergoing surgical aortic valve replacement according to current guidelines of the European Society of Cardiology (ESC) and of the American College of Cardiology Foundation/American Heart Association (ACCF/AHA). Conversely, whether the presence of CAD has any prognostic implications in elderly patients with severe AS undergoing TAVI is still a matter of debate. Of note, according to the most recent ESC guidelines on myocardial revascularisation, percutaneous revascularisation should be considered in patients undergoing TAVI with a stenosis >70% in proximal coronary segments (class IIa, level of evidence C). The aim of this article is to provide an overview of evidence supporting the need for coronary revascularisation in patients with severe AS and CAD undergoing TAVI, and to summarise optimal timing and treatment modalities for percutaneous coronary interventions in these patients.
Authors:
Giulio G Stefanini; Stefan Stortecky; Peter Wenaweser; Stephan Windecker
Related Documents :
19741024 - Determining the aetiology of pulmonary oedema by the oedema fluid-to-plasma protein ratio.
24281654 - Contrast agent bolus dispersion in a realistic coronary artery geometry: influence of o...
8074134 - Case report: recurrent pneumothorax in a patient with rheumatoid arthritis.
16077344 - Multifocal nodular lymphoid hyperplasia of the lung.
21394654 - Mitral valve damage after an aortic balloon valvuloplasty in an infant.
23893184 - Comparative study of the triton x-100-sodium deoxycholate method and detergent-enzymati...
Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology     Volume:  10     ISSN:  1969-6213     ISO Abbreviation:  EuroIntervention     Publication Date:  2014 Sep 
Date Detail:
Created Date:  2014-9-26     Completed Date:  -     Revised Date:  2014-9-27    
Medline Journal Info:
Nlm Unique ID:  101251040     Medline TA:  EuroIntervention     Country:  -    
Other Details:
Languages:  ENG     Pagination:  U69-U75     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Assessment of low-flow, low-gradient, severe aortic stenosis: an invasive evaluation is required for...
Next Document:  Coronary artery disease in patients undergoing TAVI - why not to treat.