Document Detail

Coronary artery bypass grafting with and without manipulation of the ascending aorta - a meta-analysis.
MedLine Citation:
PMID:  21511187     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: The main criticism of surgery in the SYNTAX trial was increased rate of stroke when compared to percutaneous coronary intervention. We aimed to determine whether avoiding aortic manipulation would decrease the rate of stroke.
METHOD: We performed a meta-analysis of seven studies comparing coronary artery bypass grafting (CABG) with and without manipulation of the ascending aorta.
RESULTS: When anaortic off-pump coronary artery bypass grafting (OPCAB) was compared with conventional CABG, the rate of stroke was 0.38% vs. 1.87% (p<0.0001). When anaortic OPCAB was compared with OPCAB using a side-clamp or proximal graft anastomosis device the rate of stroke was 0.31% vs. 1.35% (p=0.003).
CONCLUSION: Avoiding aortic manipulation during CABG may decrease the rate of peri-operative stroke.
J James Edelman; Tristan D Yan; Paul G Bannon; Michael K Wilson; Michael P Vallely
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Heart, lung & circulation     Volume:  20     ISSN:  1444-2892     ISO Abbreviation:  Heart Lung Circ     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-04-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100963739     Medline TA:  Heart Lung Circ     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  318-24     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Australasian Society of Cardiac and Thoracic Surgeons and the Cardiac Society of Australia and New Zealand. Published by Elsevier B.V. All rights reserved.
Cardiothoracic Surgical Unit, Royal Prince Alfred Hospital, Sydney, Australia; The Baird Institute, Sydney, Australia; Faculty of Medicine, The University of Sydney, Sydney, Australia.
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