Document Detail

Coronary artery bypass grafting in patients with left ventricular dysfunction.
MedLine Citation:
PMID:  16835984     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Coronary artery bypass grafting surgery (CABG) remains a challenge for patients with coronary artery disease and left ventricular (LV) dysfunction. The aim of this study was to evaluate the result of CABG in patients with LV dysfunction. METHODS: Medical records of 1,847 patients who underwent primary, isolated CABG at Taipei Veterans General Hospital from January 1, 1991 to December 31, 2002, were reviewed. The mortality rate associated with clinical and operative variables was compared between patients with LV ejection fraction (LVEF) > or = 35% and patients with LVEF < 35%. RESULTS: Patients with LVEF < 35% had more episodes of myocardial infarction (57.5% vs 28.9%, p < 0.001) and history of congestive heart failure (18.1% vs 3.2%, p < 0.001), higher New York Heart Association (NYHA) class, and higher angina class. Longer cardiopulmonary bypass time (147 +/- 44 minutes vs 137 +/- 40 minutes, p < 0.001) but fewer left internal mammary artery (LIMA) grafts (46.8% vs 65.7%, p < 0.001) were used in patients with LVEF < 35%. Patients with LVEF < 35% had significantly higher hospital mortality (6.6% vs 2.2%, p < 0.001), higher major morbidity (23.3% vs 16.1%, p < 0.01), and longer hospital stay (25 +/- 23 days vs 21 +/- 16 days, p < 0.01). CONCLUSION: Although patients with LV dysfunction had higher mortality and morbidity, CABG could be done in these high-risk patients with acceptable results.
Fei-Yi Wu; Yen-Chou Lu; Shiau-Ting Lai; Zen-Chung Weng; Cheng-Hsiung Huang
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of the Chinese Medical Association : JCMA     Volume:  69     ISSN:  1726-4901     ISO Abbreviation:  J Chin Med Assoc     Publication Date:  2006 May 
Date Detail:
Created Date:  2006-07-13     Completed Date:  2006-07-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  101174817     Medline TA:  J Chin Med Assoc     Country:  China (Republic : 1949- )    
Other Details:
Languages:  eng     Pagination:  218-23     Citation Subset:  IM    
Division of Cardiovascular Surgery, Department of Surgery, National Yang-Ming University School of Medicine, and Taipei Veterans General Hospital, Taiwan, ROC.
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MeSH Terms
Aged, 80 and over
Coronary Artery Bypass*
Middle Aged
Stroke Volume
Ventricular Dysfunction, Left / mortality,  physiopathology,  surgery*
Ventricular Function, Left

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