Document Detail

Coronary artery anomalies Part II: recent insights from clinical investigations.
MedLine Citation:
PMID:  15668824     Owner:  NLM     Status:  MEDLINE    
Congenital anomalies of the coronary arteries occur in 0.2-1.2% of the general population; they cause 12% of sports-related sudden cardiac deaths and 1.2% of non-sports-related deaths. We review some of the substantial advances that have been made both, in the understanding of the embryonic development of the coronary arteries and in the clinical diagnosis and management of their anomalies. In this second part of our review we elucidate recent approaches to defining coronary anomalies and provide information on their incidence and prognosis. In addition, we discuss the options for screening large populations for potentially lethal coronary malformations and elucidate the role of invasive diagnostic modalities such as intravascular ultrasound, flow wire and pressure wire. The clinical relevance of coronary anomalies is discussed particularly for the ill-defined group of anomalies that only occasionally cause severe clinical events comprising anomalous origination of a coronary artery from the opposite sinus (ACAOS), coronary artery fistulae and myocardial bridging. Finally, we provide an update on current diagnostic and therapeutic recommendations.
Y von Kodolitsch; O Franzen; G K Lund; D H Koschyk; W D Ito; T Meinertz
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Zeitschrift für Kardiologie     Volume:  94     ISSN:  0300-5860     ISO Abbreviation:  Z Kardiol     Publication Date:  2005 Jan 
Date Detail:
Created Date:  2005-01-25     Completed Date:  2005-05-31     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0360430     Medline TA:  Z Kardiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1-13     Citation Subset:  IM    
Clinic of Internal Medicine III, University Hospital Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.
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MeSH Terms
Arrhythmias, Cardiac / epidemiology,  etiology
Cause of Death
Coronary Stenosis / congenital,  diagnosis,  embryology
Coronary Vessel Anomalies / diagnosis,  embryology,  mortality*
Cross-Sectional Studies
Death, Sudden, Cardiac / epidemiology*,  etiology,  prevention & control
Diagnostic Imaging
Exercise Test
Sinus of Valsalva / abnormalities,  embryology

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