Document Detail

Coronary arteriographic findings in symptomatic and asymptomatic subjects with coronary artery calcification.
MedLine Citation:
PMID:  11578702     Owner:  NLM     Status:  MEDLINE    
The relation of coronary artery calcification with the presence of symptoms of coronary artery disease and its angiographic severity is not clear. We studied 37 apparently healthy, asymptomatic subjects that were found by digital cinefluoroscopy to have coronary calcium and compared to age- and sex-matched group of patients with coronary calcium and symptomatic coronary artery disease. Normal coronary arteries and non-obstructive lesions only were found in 12/37 (32.4%) and 11/37 (29.7%) asymptomatic subjects vs. 1/37 (2.7%) and 2/37 (5.4%) patients; P<0.001 and P<0.012, respectively. Obstructive lesions were more rare in asymptomatic subjects than in patients, 14/37 (37.8%) vs. 34/37 (91.9%) (P<0.0001), as well as total occlusions, 2/37 (5.4%) vs. 10/37 (27%) (P<0.024). Median worst lesion stenosis was 30% in asymptomatic subjects and 95% in patients (P<0.0001). In asymptomatic usual cardiovascular risk subjects, coronary calcium detection by digital cinefluoroscopy is accompanied by a relatively high probability of obstructive disease, although less severe angiographically than in age- and sex-matched catheterized patients with symptomatic coronary artery disease.
D Alexopoulos; T Toulgaridis; G Sitafidis; J Christodoulou; C Stathopoulos; G Hahalis
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of cardiology     Volume:  80     ISSN:  0167-5273     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:    2001 Sep-Oct
Date Detail:
Created Date:  2001-10-01     Completed Date:  2001-12-18     Revised Date:  2006-07-12    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  117-21; discussion 121-3     Citation Subset:  IM    
Division of Cardiology, Department of Medicine, Patras University Hospital, 26500 Patras, Rio, Greece.
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MeSH Terms
Calcinosis / complications,  radiography*
Coronary Angiography / methods*
Coronary Disease / complications,  radiography*
Middle Aged
Risk Factors
Sensitivity and Specificity

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