Document Detail

Coronary arterial spasm versus esophageal spasm. Response to ergonovine.
MedLine Citation:
PMID:  7234895     Owner:  NLM     Status:  MEDLINE    
In this report we show that coronary arterial and esophageal spasm are sometimes clinically indistinguishable. Pain patterns can be identical, nitroglycerin can bring relief, interval electrocardiograms and exercise electrocardiograms generally disclose no abnormalities, coronary arteriograms may be within normal limits or nearly so, and, importantly, an ergonovine provocative test can provoke esophageal spasm accompanied by pain mistaken for Prinzmetal's angina. Accordingly, chest pain in response to the administration of ergonovine is not evidence of coronary arterial spasm without simultaneous arteriographic proof together with changes in the monitoring electrocardiogram. Conversely, gastroenterologists should not expose patients to the risk of ergonovine without prior assurance that the coronary arterial response is normal. Our observations illustrate these points and identify a patient with symptomatic esophageal spasm previously diagnosed as Prinzmetal's angina.
F N Gravino; J K Perloff; L A Yeatman; A F Ippolitti
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The American journal of medicine     Volume:  70     ISSN:  0002-9343     ISO Abbreviation:  Am. J. Med.     Publication Date:  1981 Jun 
Date Detail:
Created Date:  1981-07-23     Completed Date:  1981-07-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0267200     Medline TA:  Am J Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1293-6     Citation Subset:  AIM; IM    
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MeSH Terms
Angina Pectoris / diagnosis*
Angina Pectoris, Variant / diagnosis*
Atropine / therapeutic use
Diagnosis, Differential
Ergonovine / adverse effects,  diagnostic use*
Esophageal Diseases / diagnosis*
Middle Aged
Pain / chemically induced,  drug therapy
Spasm / diagnosis*
Reg. No./Substance:
51-55-8/Atropine; 60-79-7/Ergonovine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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