Document Detail

Coronary arterial plaque characterized by multislice computed tomography predicts complications following coronary intervention.
MedLine Citation:
PMID:  17379976     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: A reliable, noninvasive assessment of plaque configuration would constitute an important step forward for predicting complications following percutaneous coronary intervention (PCI). Multislice computed tomography (MSCT) holds promise with respect to allowing for differentiation of coronary lesion configuration. However, it has not yet been clarified whether the characteristics of coronary artery plaque measured by MSCT predict complications after PCI. The aim of this study was to investigate the relationship between plaque configuration and complications after coronary intervention in patients with stable angina pectoris. METHODS: MSCT was performed in patients with angina pectoris who were scheduled for PCI prospectively, and 26 patients (70 +/- 11 years, 18 males) with coronary artery plaque in a stenotic coronary artery measured by MSCT were recruited for this study. Thirty-five plaques in the stenotic coronary lesions were divided into 3 groups based on the CT density as soft, intermediate, and hard, and were compared with the complications after PCI. RESULTS: The soft plaque group before PCI (n = 11) was significantly associated with the appearance of slow flow (n = 4) or a compromised side branch (n = 1) after PCI, whereas the hard plaque group before PCI (n = 17) was associated with the appearance of dissection (n = 2) or perforation (n = 1) after PCI (P = 0.004). The intermediate plaque group (n = 7) had only one complication, a compromised side branch (n = 1). CONCLUSION: Coronary arterial plaque characterized by MSCT can predict intervention-related complication. It may be important for the risk stratification of the patients scheduled to undergo PCI to investigate plaque configuration by MSCT.
Yukihiko Kinohira; Yasushi Akutsu; Hui-Ling Li; Yuji Hamazaki; Masayuki Sakurai; Yuka Saiki; Yusuke Kodama; Hideki Nishimura; Hideyuki Yamanaka; Akira Shinozuka; Takehiko Gokan; Takashi Katagiri
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International heart journal     Volume:  48     ISSN:  1349-2365     ISO Abbreviation:  -     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2007-03-23     Completed Date:  2007-09-27     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  101244240     Medline TA:  Int Heart J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  25-33     Citation Subset:  IM    
Third Department of Internal Medicine (Division of Cardiology), Showa University School of Medicine, Shinagawa-ku, Tokyo, Japan.
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MeSH Terms
Angina Pectoris / radiography,  therapy*
Angioplasty, Transluminal, Percutaneous Coronary / adverse effects*
Coronary Angiography
Coronary Artery Disease / etiology,  prevention & control,  radiography*
Follow-Up Studies
Prospective Studies
Reproducibility of Results
Tomography, X-Ray Computed / methods*

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