Document Detail


Coronary angiography with multi-slice computed tomography.
MedLine Citation:
PMID:  11558487     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: A new generation of subsecond multi-slice computed tomography (MSCT) scanners, which allow complete coronary coverage, are becoming widely available. We investigated the potential value of MSCT angiography in a range of coronary disorders. METHODS: We studied 35 patients, including 11 who had undergone percutaneous transluminal coronary angioplasty and four who had had coronary-artery bypass grafts, by both MSCT and conventional coronary angiography. After intravenous injection of a non-ionic contrast medium with high iodine content, the entire heart was scanned within a single breath-hold. The total examination time was no more than 20 min. The retrospective electrocardiographically gated reconstruction source images and three-dimensional reconstructed volumes were analysed by two investigators, unaware of the results of conventional angiography. FINDINGS: In the 31 patients without previous coronary surgery, 173 (73%) of the 237 proximal and middle coronary segments were assessable. In the assessable segments, 17 of 21 significant stenoses (>50% reduction of vessel diameter) were correctly diagnosed. The non-assessable segments included four lesions. Misinterpretations were mainly the result of severe calcification of the vessel wall. Segments with implanted stents were poorly visualised, but stent patency could be assessed in all cases. Of the 17 segments of bypass grafts, 15 were assessable and four of five graft lesions were detected. Two cases of anomalous coronary anatomy could be visualised well. INTERPRETATION: These preliminary data suggest that MSCT allows non-invasive imaging of coronary-artery stenoses and has potential to develop into a reliable clinical technique.
Authors:
K Nieman; M Oudkerk; B J Rensing; P van Ooijen; A Munne; R J van Geuns; P J de Feyter
Related Documents :
7267507 - Electrocardiographic changes following a cardiac stab wound. case report and review of ...
23899887 - Myocardial dimensions and hemodynamics during 24-h ultraendurance ergometry.
23909987 - Early statin therapy in acute myocardial infarction.
12809417 - Measurement of the rt interval on ecg records during electron-beam ct.
7501577 - Unstable angina pectoris. what is the likelihood of further cardiac events?
6460197 - Acute effects of haemodialysis on left heart dimensions and left ventricular function: ...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Lancet     Volume:  357     ISSN:  0140-6736     ISO Abbreviation:  Lancet     Publication Date:  2001 Feb 
Date Detail:
Created Date:  2001-09-17     Completed Date:  2001-09-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  England    
Other Details:
Languages:  eng     Pagination:  599-603     Citation Subset:  AIM; IM    
Affiliation:
Department of Cardiology, Thoraxcenter, Rotterdam University Hospital, Netherlands.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Coronary Angiography / methods*
Coronary Disease / diagnosis*,  pathology
Female
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Reproducibility of Results
Retrospective Studies
Tomography, X-Ray Computed / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Risk of lipodystrophy in HIV-1-infected patients treated with protease inhibitors: a prospective coh...
Next Document:  Impaired fatty acid oxidation in propofol infusion syndrome.