Document Detail


Coronary angiographic findings in various types of unstable angina--study on the pathophysiology of unstable angina.
MedLine Citation:
PMID:  6834648     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Coronary angiographic findings were studied in 129 patients with various types of unstable angina in order to clarify the pathophysiology of unstable angina. The subjects were divided into 3 types: effort angina (E), rest angina (R), and effort and rest angina (E+R), and each of these 3 types was subdivided into group I (new onset), II (recurrent) and III (changing pattern). 1) R had less severe coronary lesions than E or E+R. 2) Severity and distribution of coronary atherosclerotic lesions in unstable angina were similar to those in stable angina. 3) Incidence of coronary spasm is higher in unstable R and E+R than in stable R and E+R, respectively. 4) Unstable R and E+R with frequent attacks were associated with a higher frequency of coronary spasm and severe proximal coronary stenosis than those without frequent attacks, respectively. 5) Among unstable E+R-III (changing pattern), the patients who developed E+R from E showed significantly higher incidence of multiple vessel disease than those who developed E+R from R and significantly lower incidence of spontaneous spasm than those with E+R, who remained with the same pattern but in whom the frequency and/or the intensity of the attack increased, without any significant difference in the severity of coronary stenosis from other 2 subgroups. It is concluded that coronary spasm as well as severe coronary atherosclerotic lesions may be responsible for the unstable state of angina. Especially in R and E+R, coronary spasm is the most important factor responsible for the unstabilization of angina.
Authors:
J Fujii; T Aizawa; K Ogasawara; S Ono; H Sawada; A Okabe; M Kuboki; H Asanoi; H Watanabe; A Ohta; S Koyama; K Kato
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Japanese circulation journal     Volume:  47     ISSN:  0047-1828     ISO Abbreviation:  Jpn. Circ. J.     Publication Date:  1983 Apr 
Date Detail:
Created Date:  1983-05-27     Completed Date:  1983-05-27     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7806868     Medline TA:  Jpn Circ J     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  440-50     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Angina Pectoris / etiology,  physiopathology*,  radiography
Coronary Angiography*
Coronary Vasospasm / complications
Female
Humans
Male
Middle Aged
Physical Exertion
Rest

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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