Document Detail

Coronary spasm in neurosurgical patients and role of trigeminocardiac reflex.
MedLine Citation:
PMID:  24587903     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Background. Coronary artery spasm (CAS) is a rarely reported complication in neurosurgical patients and its main causative mechanism was attributed to vagal mediated responses. However, these may be the unusual manifestations of trigeminal cardiac reflex (TCR) which is a well established brain stem reflex observed in various neurosurgical patients. Methods and Results. In this review, we have searched for the case reports/papers related to intraoperative coronary spasm in neurosurgical patients and described the role of TCR in this regard. TCR is a possible mechanism in producing CAS in most of the cases in which stimulation occurred at or near the vicinity of trigeminal nerve. It is likely that TCR mediated coronary spasm may be a physiological mechanism and not related to actual myocardial insult apparent by cardiac enzymes or echocardiography studies in most of the cases. Some common risk factors may also exist related to occurrence of CAS as well as TCR. Conclusions. In conclusion, neurosurgical procedures occurring at the vicinity of trigeminal nerve may produce CAS even in previously healthy patients and may produce catastrophic consequences. There is a need for future reports and experimental studies on the interaction of TCR and pathophysiological mechanisms related to CAS.
Tumul Chowdhury; Cyrill Meuwly; Nora Sandu; Ronald B Cappellani; Bernhard Schaller
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Publication Detail:
Type:  Journal Article; Review     Date:  2014-01-27
Journal Detail:
Title:  Neurology research international     Volume:  2014     ISSN:  2090-1852     ISO Abbreviation:  Neurol Res Int     Publication Date:  2014  
Date Detail:
Created Date:  2014-03-03     Completed Date:  2014-06-24     Revised Date:  2014-06-24    
Medline Journal Info:
Nlm Unique ID:  101543314     Medline TA:  Neurol Res Int     Country:  United States    
Other Details:
Languages:  eng     Pagination:  974930     Citation Subset:  -    
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