| Corneal ulceration due to vitamin A deficiency in Zellweger syndrome. | |
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MedLine Citation:
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PMID: 19541270 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report a case of vitamin A deficiency and secondary corneal ulcer in an infant with Zellweger syndrome. A 7-month-old infant with failure to thrive and malnutrition developed a corneal ulcer. Fortified antibiotic eye drops were administered without improvement. Vitamin A deficiency was suspected and confirmed. Supplementation with oral vitamin A decreased corneal opacification. Zellweger syndrome was later diagnosed. Vitamin A deficiency should be considered in the differential diagnosis of nonhealing corneal ulcers in children, especially those with systemic syndromes and failure to thrive. |
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Authors:
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Jeffrey D Colburn; Anna S Skelo; Sean P Donahue |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus Volume: 13 ISSN: 1528-3933 ISO Abbreviation: J AAPOS Publication Date: 2009 Jun |
Date Detail:
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Created Date: 2009-06-22 Completed Date: 2009-09-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9710011 Medline TA: J AAPOS Country: United States |
Other Details:
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Languages: eng Pagination: 289-91 Citation Subset: IM |
Affiliation:
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Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Oral Corneal Ulcer / diagnosis, etiology* Diagnosis, Differential Female Humans Infant Vitamin A / administration & dosage Vitamin A Deficiency / complications*, diagnosis, drug therapy Vitamins / administration & dosage Zellweger Syndrome / complications*, diagnosis |
| Chemical | |
Reg. No./Substance:
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0/Vitamins; 11103-57-4/Vitamin A |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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