| Corneal silver deposits following Crede's prophylaxis an examination with electron dispersive x-ray analysis (EDX-analysis) and scanning electron microscope (SEM). | |
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MedLine Citation:
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PMID: 2100171 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In a case of silver nitrate injury after Credé's prophylaxis, the cornea of a newborn presented yellow-brown, lime-like plaques on the nasal part of the right eye. A paracentral ulcerating stromal opacification undermined these appositions, when the patient was admitted to the eye-clinic at Aachen. In the material obtained by a lamellar keratectomy scanning electron microscopical examination was able to prove the existence of granules, previously described in light-microscopy. These granules measured 100 to 300 nm in diameter. An earlier chemical analysis of necrotic material showed no silver specific reaction. By means of EDX-analysis these granules could be identified as silver-containing. Injuries by silver nitrate solutions used for Credé's prophylaxis are seldom but still reported. The mechanism of injury in this case of a child, born by sectio remains unknown. Neither the use of an unusual silver nitrate solution, that was taken from a disposable ampoule (Mova-Nitrat R) was reported, nor any corneal injury during sectio mentioned. Nevertheless the method of EDX-analysis and SEM proved the diagnosis of corneal silver deposits, so that the origin of the granullar opacification of the cornea could be determined. |
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Authors:
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G Schirner; N F Schrage; S Salla; C Teping; M Reim; W G Burchard; B Schwab |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Lens and eye toxicity research Volume: 7 ISSN: 1042-6922 ISO Abbreviation: Lens Eye Toxic Res Publication Date: 1990 |
Date Detail:
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Created Date: 1991-08-20 Completed Date: 1991-08-20 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8916639 Medline TA: Lens Eye Toxic Res Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 445-57 Citation Subset: IM |
Affiliation:
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Augenklinik, RWTH Aachen. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cornea
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chemistry*,
ultrastructure Corneal Opacity / chemically induced*, metabolism, pathology, surgery Electron Probe Microanalysis Eye Infections / prevention & control Humans Infant, Newborn Microscopy, Electron, Scanning Silver / analysis* Silver Nitrate / adverse effects*, therapeutic use |
| Chemical | |
Reg. No./Substance:
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7440-22-4/Silver; 7761-88-8/Silver Nitrate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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