Document Detail


Corneal infection after radial keratotomy.
MedLine Citation:
PMID:  9559468     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To evaluate nine eyes that developed corneal infection after radial keratotomy (RK) and their subsequent management. SETTING: Dr. Rajendra Prasad Centre for Ophthalmic Sciences, New Delhi, India. METHOD: The parameters evaluated were interval between RK and development of the ulcer, number of keratotomy incisions, nature of surgery (primary or secondary), status at presentation, and best corrected visual acuity (BCVA). Corneal scrapings were taken from all eyes for microbiological evaluation. Initial therapy was based on clinical impression and subsequent therapy, on the microbiological report. RESULTS: Staphylococcus species were the most frequently isolated bacteria followed by Pseudomonas aeruginosa. Two eyes had fungal growth, and no organisms were isolated from one. All but one eye responded to medical therapy; healing took 23 to 26 days. Therapeutic penetrating keratoplasty (PKP) was done in one eye. Presenting BCVA of hand movement to 6/36 improved to hand movement to 6/18 after the ulcer healed. Final BCVA was 6/36 to 6/9 after lamellar keratoplasty or PKP or with contact lens of spectacle correction. CONCLUSION: Our study shows that corneal infection is a potential complication of RK. Therefore, persistent postoperative irritation should be carefully observed to ensure early diagnosis and prompt therapy.
Authors:
A Panda; G K Das; M Vanathi; A Kumar
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of cataract and refractive surgery     Volume:  24     ISSN:  0886-3350     ISO Abbreviation:  J Cataract Refract Surg     Publication Date:  1998 Mar 
Date Detail:
Created Date:  1998-05-19     Completed Date:  1998-05-19     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8604171     Medline TA:  J Cataract Refract Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  331-4     Citation Subset:  IM    
Affiliation:
Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aspergillosis / drug therapy,  etiology*
Bacteria / isolation & purification
Cefazolin / therapeutic use
Cornea / microbiology
Corneal Ulcer / drug therapy,  microbiology*
Drug Therapy, Combination
Eye Infections / drug therapy,  etiology*
Female
Fungi / isolation & purification
Humans
Keratoplasty, Penetrating
Keratotomy, Radial / adverse effects*
Male
Natamycin / therapeutic use
Ophthalmic Solutions
Pseudomonas Infections / drug therapy,  etiology*
Staphylococcal Infections / drug therapy,  etiology*
Tobramycin / therapeutic use
Visual Acuity
Chemical
Reg. No./Substance:
0/Ophthalmic Solutions; 25953-19-9/Cefazolin; 32986-56-4/Tobramycin; 7681-93-8/Natamycin

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