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Corneal Melanoma: Report of Three Cases.
MedLine Citation:
PMID:  22169880     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVES:: We report three cases of corneal melanoma: two without conjunctival primary acquired melanosis or melanoma and one with a history of conjunctival melanoma. METHODS:: Report of 3 cases with corneal melanoma and literature review. RESULTS:: Medical records of three patients with the diagnosis of corneal melanoma were reviewed. Total excisional biopsy with corneal epitheliectomy using 20% ethanol was performed. Postoperative topical chemotherapy with 0.04% mitomycin-C was used for 4 weeks as adjunctive therapy. The follow-up ranged from 13 months to 7 years. Each of the two patients experienced two recurrences. One was treated in a fashion similar to that of the initial tumor, and the other was treated by enucleation. None of the patients developed regional or distant metastasis. CONCLUSIONS:: Malignant melanoma can rarely occur on the cornea with no contiguous conjunctival component. Eye-conserving treatment should be attempted first. Recurrences may occur, and a close follow-up is necessary.
Authors:
Omür Uçakhan-Gündüz; Kaan Gündüz; Melisa Z Karsloğlu; Aylin Okçu-Heper; Ayfer Kanpolat
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-12-13
Journal Detail:
Title:  Eye & contact lens     Volume:  -     ISSN:  1542-233X     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101160941     Medline TA:  Eye Contact Lens     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
From the Department of Ophthalmology (Ö.U.G., K.G., A.K., M.Z.K.), Ankara University Faculty of Medicine, Ankara, Turkey; Department and Department of Pathology (A.O-H.), Ankara University Faculty of Medicine, Ankara, Turkey.
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