Document Detail


Corneal light transmission and roughness after refractive surgery.
MedLine Citation:
PMID:  20453696     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To determine the relation between the corneal light transmission measurements and the epithelial surface properties in hen corneas after different refractive surgery techniques photorefractive keratectomy, laser in situ keratomileusis, and laser-assisted subepithelial keratomileusis, and a group with only epithelial corneal removal (deepithelialization). METHODS: Five groups of hen corneas with different treatments and a control group were analyzed at 30 days. Direct transmittance and corneal light scattering were measured by a scatterometer developed by our group. Quantitative and systematic measurements of external and internal roughness and epithelium thickness were assessed using standard techniques developed for quantitative analysis of microphotographs of the corneal epithelium. RESULTS: Data analysis revealed that the roughness in the epithelial surface was associated with the corneal light transmission. The direct transmittance of light showed a significant correlation with the epithelial roughness in the control (r = -0.99, p < 0.05) and photorefractive keratectomy (r = -0.99, p < 0.05) groups. However, there was no relation between the epithelial thickness and the corneal light transmission measurements. CONCLUSIONS: The experimental results suggested that the roughness of the epithelial surfaces is related to the light transmission in the cornea.
Authors:
Pablo Pérez-Merino; M Carmen Martinez-Garcia; Santiago Mar-Sardaña; Alfonso Pérez-Escudero; Tomas Blanco-Mezquita; Agustin Mayo-Iscar; Jesus Merayo-Lloves
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Optometry and vision science : official publication of the American Academy of Optometry     Volume:  87     ISSN:  1538-9235     ISO Abbreviation:  Optom Vis Sci     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-05     Completed Date:  2010-10-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8904931     Medline TA:  Optom Vis Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  E469-74     Citation Subset:  IM    
Affiliation:
Instituto Universitario de Oftalmobiología Aplicada, Department of Cell Biology, Faculty of Medicine, University of Valladolid, Valladolid, Spain. p.perez@io.cfmac.csic.es
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MeSH Terms
Descriptor/Qualifier:
Animals
Chickens
Cornea / pathology,  physiopathology*,  radiation effects,  surgery*
Epithelium, Corneal / surgery
Female
Keratectomy, Subepithelial, Laser-Assisted
Keratomileusis, Laser In Situ
Light*
Photorefractive Keratectomy
Postoperative Period
Refractive Surgical Procedures*
Scattering, Radiation

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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