Document Detail


Corneal biomechanical properties and intraocular pressure in high myopic anisometropia.
MedLine Citation:
PMID:  20531203     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: To investigate corneal biomechanical properties and intraocular pressure (IOP) in patients with high myopic anisometropia. METHODS: Patients with high myopic anisometropia (n = 23) and emmetropic subjects (n = 55) were enrolled. Corneal hysteresis (CH), Goldmann-correlated intraocular pressure (IOPg), corneal resistance factor, and corneal-compensated IOP (IOPcc) were measured with Ocular Response Analyzer. Central corneal thickness was measured by optical coherence tomography. Zeiss IOL-Master determined the values of corneal refractive power and ocular axial length. RESULTS: Significant differences were presented in CH, IOPg, and IOPcc among the high myopic, contralateral, and normal eyes (analysis of variance, P<0.05). CH in high myopic eye was lower than that in the other two groups (post hoc, P<0.05), whereas IOPg and IOPcc in both eyes of anisometropic myopia were higher compared with the normal subjects (post hoc, P<0.01). CH was associated with central corneal thickness and axial length in high myopic eyes. All measured biometric parameters showed significant correlations between two eyes in high myopic anisometropia. CONCLUSIONS: High myopic eyes showed decreased CH, but not corneal resistance factor, which indicates that some aspects of corneal biomechanical properties may be altered in high myopic eye of anisometropia. It is also suggested that anisometropic eyes with different refractive errors do not share the same biomechanical properties, which may impact IOP measurement.
Authors:
Suzhong Xu; Aiqin Xu; Aizhu Tao; Jianhua Wang; Fan Fan; Fan Lu
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Eye & contact lens     Volume:  36     ISSN:  1542-233X     ISO Abbreviation:  Eye Contact Lens     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-08     Completed Date:  2010-10-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101160941     Medline TA:  Eye Contact Lens     Country:  United States    
Other Details:
Languages:  eng     Pagination:  204-9     Citation Subset:  IM    
Affiliation:
School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical College, Wenzhou, Zhejiang, China.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Anisometropia / complications*,  pathology,  physiopathology
Biomechanics
Cornea / pathology,  physiopathology*
Female
Humans
Intraocular Pressure / physiology*
Male
Middle Aged
Myopia / complications*,  pathology,  physiopathology
Severity of Illness Index
Tomography, Optical Coherence
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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