| Core-shell NaYF(4):Yb(3+),Tm(3+)@Fe(x)O(y) nanocrystals for dual-modality T(2)-enhanced magnetic resonance and NIR-to-NIR upconversion luminescent imaging of small-animal lymphatic node. | |
| | |
MedLine Citation:
|
PMID: 21742376 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
New core-shell structured NaYF(4):Yb(3+),Tm(3+)@Fe(x)O(y) nanocrystals, with 20 nm Yb(3+),Tm(3+)-co-doped NaYF(4) nanocrystals as a core and 5 nm Fe(x)O(y) nanocrystals as a shell, have been synthesized and characterized by TEM and XRD analysis. These core-shell nanocrystals exhibit excellent near-infrared upconversion luminescence (UCL) emission at 800 nm under excitation by a continuous-wave 980 nm laser and superparamagnetic properties with a saturation magnetization (Ms) of ∼12 emu/g. Water-soluble nanocrystals were obtained by surface ligand exchange of oleic acid-coated precursor nanocrystals, and their internalization within living cells has been investigated by laser scanning UCL microscopy. Furthermore, the obtained core-shell nanocrystals have been applied in dual-modality T(2)-enhanced magnetic resonance (MR) and UCL imaging in vivo of the lymphatic system. Moreover, the toxicity of NaYF(4):Yb(3+),Tm(3+)@Fe(x)O(y) nanocrystals has also been evaluated by MTT assay, IC50 values, and histological analysis of lymphatic node sections. |
| | |
Authors:
|
Ao Xia; Yuan Gao; Jing Zhou; Chunyan Li; Tianshe Yang; Dongmei Wu; Limin Wu; Fuyou Li |
Related Documents
:
|
8311956 - Magnetic resonance imaging of granulomatous inflammations: sarcoidosis and tuberculosis. 3986146 - Some factors influencing interobserver variation in classifying simple pneumoconiosis. 21481556 - A systematic comparison of two pulse sequences for edema assessment in mr-mammography. 8062126 - Chondrosarcoma complicating synovial chondromatosis: findings with magnetic resonance i... 20077476 - Differentiating vascular parkinsonism from idiopathic parkinson's disease: a systematic... 3591926 - Interaction between magnetic fields and metallic ossicular prostheses. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-7-8 |
Journal Detail:
|
Title: Biomaterials Volume: - ISSN: 1878-5905 ISO Abbreviation: - Publication Date: 2011 Jul |
Date Detail:
|
Created Date: 2011-7-11 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8100316 Medline TA: Biomaterials Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 Elsevier Ltd. All rights reserved. |
Affiliation:
|
Advanced Materials Laboratory & Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, PR China. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Enhanced bone-integration capability of alkali- and heat-treated nanopolymorphic titanium in micro-t...
Next Document: The sex-specific effects of famine on the association between placental size and later hypertension.