Document Detail


Core body temperature and the thermoneutral zone: a longitudinal study of normal human pregnancy.
MedLine Citation:
PMID:  21087419     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Aim:  Using a longitudinal study design, we investigated changes in maternal core temperature and ambient temperatures before and after a localized cooling procedure to the right hand. Methods:  Fifteen pregnant women participated. The experiments were sequentially performed for 21 month periods on each subject: from the 8th week of gestation to 1 year after delivery on seven separate occasions (gestational weeks 8, 16, 26, 36 and 12, 24, 52 weeks post-partum). The experiments were conducted in a climactic chamber, allowing ambient temperature adjustment to each subjects' thermoneutral zone determined using Doppler ultrasound of the digital artery. Results:  Maternal core temperature decreased from 37.1 °C (week 8) towards term, reaching a nadir (36.4 °C) at 12 weeks post-partum (P < 0.001). The ambient temperature required to reach the thermoneutral zone changed significantly from 26.5 °C (week 8) falling to its lowest point: 23.0 °C (week 36) (P < 0.001), then stabilized from 24 weeks post-partum. Conclusion:  Maternal core temperature is highest in the first trimester but falls during pregnancy to a nadir 3 months post-partum. The ambient temperature required to reach the thermoneutral zone was 4 °C lower at 36 weeks of gestation compared with early pregnancy and late post-partum. Human temperature regulation is altered in pregnancy and for at least 3 months post-partum.
Authors:
T W Hartgill; T K Bergersen; J Pirhonen
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Publication Detail:
Type:  Journal Article     Date:  2011-01-19
Journal Detail:
Title:  Acta physiologica (Oxford, England)     Volume:  201     ISSN:  1748-1716     ISO Abbreviation:  Acta Physiol (Oxf)     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-03-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101262545     Medline TA:  Acta Physiol (Oxf)     Country:  England    
Other Details:
Languages:  eng     Pagination:  467-74     Citation Subset:  IM    
Copyright Information:
© 2011 The Authors. Acta Physiologica © 2011 Scandinavian Physiological Society.
Affiliation:
Department of Obstetrics and Gynaecology, Oslo University Hospital, Oslo, Norway  University of Oslo, Oslo, Norway  Department of Dermatology, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
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