Document Detail

Cord colitis syndrome in cord-blood stem-cell transplantation.
MedLine Citation:
PMID:  22168655     Owner:  NLM     Status:  In-Data-Review    
To the Editor: According to Herrera et al. (Sept. 1 issue),(1) the cord colitis syndrome is distinct from graft-versus-host disease (GVHD). We think that this conclusion lacks the evidence needed for defining a new disease entity and that its manifestations are concordant with a delayed GVHD reaction. Late colitis associated with high mortality was first described in mice after allogeneic and xenogeneic (rat) bone marrow transplantation.(2) This colitis in mice was responsive to antibiotics.(3) Furthermore, the histopathological findings in the cord colitis syndrome are consistent with the lesions described in monkeys and mice with chronic GVHD(4) and are not at . . .
Dirk van Bekkum; Jaak Vossen; Chris Zurcher
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The New England journal of medicine     Volume:  365     ISSN:  1533-4406     ISO Abbreviation:  N. Engl. J. Med.     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0255562     Medline TA:  N Engl J Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2336-8     Citation Subset:  AIM; IM    
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