Document Detail

Cord blood levels of corticotropin-releasing factor.
MedLine Citation:
PMID:  2950934     Owner:  NLM     Status:  MEDLINE    
The levels of corticotropin-releasing factor (CRF) in the cord blood from 34 infants were determined by radioimmunoassay. All infants were born by vaginal delivery after an uneventful pregnancy. Levels of cortisol, dehydroepiandrosterone sulfate and ACTH were high in the cord blood. CRF levels (mean +/- SD) were 100.5 +/- 31.7 and 44.5 +/- 7.8 pg/ml, respectively, in cord blood and in controls (healthy prepubertal children, n = 10). Although the origin of CRF in peripheral circulation has not been clarified, we speculate that the high adrenocortical steroid synthesis of the fetus might be a consequence of high CRF levels in fetal circulation.
K Nagashima; H Yagi; H Yunoki; T Noji; T Kuroume
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biology of the neonate     Volume:  51     ISSN:  0006-3126     ISO Abbreviation:  Biol. Neonate     Publication Date:  1987  
Date Detail:
Created Date:  1987-05-20     Completed Date:  1987-05-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0247551     Medline TA:  Biol Neonate     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  1-4     Citation Subset:  IM    
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MeSH Terms
Corticotropin-Releasing Hormone / blood*
Dehydroepiandrosterone / analogs & derivatives,  blood
Dehydroepiandrosterone Sulfate
Fetal Blood / analysis*
Hydrocortisone / blood
Infant, Newborn
Reg. No./Substance:
50-23-7/Hydrocortisone; 53-43-0/Dehydroepiandrosterone; 651-48-9/Dehydroepiandrosterone Sulfate; 9015-71-8/Corticotropin-Releasing Hormone

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