Document Detail

Copper-catalyzed aldol-type addition of ketones to aromatic nitriles: a simple approach to enaminone synthesis.
MedLine Citation:
PMID:  23450129     Owner:  NLM     Status:  Publisher    
An efficient method for the synthesis of enaminones is described. The aldol-type addition of ketones to aromatic nitriles proceeded smoothly in the presence of a simple copper catalyst system (CuI-2,2'-bipyridine-NaOtBu) in N,N-dimethylformamide. Enaminones in satisfactory to excellent yields were produced using this technique.
Xiaoqiang Yu; Longxiang Wang; Xiujuan Feng; Ming Bao; Yoshinori Yamamoto
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-3-1
Journal Detail:
Title:  Chemical communications (Cambridge, England)     Volume:  -     ISSN:  1364-548X     ISO Abbreviation:  Chem. Commun. (Camb.)     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-3-1     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610838     Medline TA:  Chem Commun (Camb)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116023, China.
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