Document Detail

Copper-Mediated Aerobic Fluoroalkylation of Arylboronic Acids with Fluoroalkyl Iodides at Room Temperature.
MedLine Citation:
PMID:  22458339     Owner:  NLM     Status:  Publisher    
A copper-mediated ligandless aerobic fluoroalkylation of aryl boronic acids under mild conditions was described, for the first time. The reaction tolerates a wide range of functional groups, thus allowing for further transformation. Mechanistic studies suggest that [RfCu] was the active copper species that formed the desired perfluoroalkylarenes and [RfCu] was generated from [PhCu] either by a oxidative-addition/reductive-elimination mechanism or by a nucleophilic substitution via a halogen "ate'' inte-rmediate.
Qingqing Qi; Qilong Shen; Long Lu
Related Documents :
22582939 - Pdcl(2)-catalyzed oxidative cycloisomerization of 3-cyclopropylideneprop-2-en-1-ones.
22424139 - Palladium-catalyzed dehydrogenative β'-functionalization of β-keto esters with indole...
19852469 - Novel juvenogens (insect hormonogenic agents): preparation and biological tests on neob...
22907919 - Enantioselective organocatalyzed cascade reactions to highly functionalized spirotetrac...
22807209 - α,n-didehydrotoluenes by photoactivation of (chlorobenzyl)trimethylsilanes: an alterna...
8138119 - Involvement of growth hormone and prolactin in the induction of vitellogenin synthesis ...
6298529 - Compounds of novel structure having kappa-agonist behavioral effects in rhesus monkeys.
22582939 - Pdcl(2)-catalyzed oxidative cycloisomerization of 3-cyclopropylideneprop-2-en-1-ones.
21374029 - Microtiter plate technique for the measurement of glutathione in fresh and cryopreserve...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-3-29
Journal Detail:
Title:  Journal of the American Chemical Society     Volume:  -     ISSN:  1520-5126     ISO Abbreviation:  -     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-3-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7503056     Medline TA:  J Am Chem Soc     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Host-pathogen interactome mapping for HTLV-1 and -2 retroviruses.
Next Document:  Measuring sidewalk distances using Google Earth.