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Copper (I) Hydroxyapatite Catalyzed Sonogashira Reaction of Alkynes with Styrenyl Bromides. Reaction of Cis-Styrenyl Bromides Forming Unsymmetric Diynes.
MedLine Citation:
PMID:  23025420     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
An efficient Sonogashira coupling of terminal alkynes and styrenyl bromides has been achieved under the catalysis of hydroxyapatite-supported copper (I). The trans-styrenyl bromides produce the usual trans-en-yne products, whereas the cis- styrenyl bromides lead to unsymmetric 1,3-diynes by the cross coupling of terminal alkyne and the alkyne generated from the cis-styrenyl bromide. A series of trans-en-ynes and unsymmetric 1,3-diynes have been synthesized by this protocol.
Authors:
Debasree Saha; Tanmay Chatterjee; Manabendra Mukherjee; Brindaban Chandra Ranu
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-2
Journal Detail:
Title:  The Journal of organic chemistry     Volume:  -     ISSN:  1520-6904     ISO Abbreviation:  J. Org. Chem.     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985193R     Medline TA:  J Org Chem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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