Document Detail

Copper-assisted palladium(II)-catalyzed direct arylation of cyclic enaminones with arylboronic acids.
MedLine Citation:
PMID:  23088256     Owner:  NLM     Status:  MEDLINE    
Described herein is a palladium(II)-catalyzed direct arylation of cyclic enaminones with arylboronic acids. The versatility of this method is that both electron-rich and electron-poor boronic acids can be coupled in high yields. A mixture of two Cu(II) additives was crucial for efficient cross-coupling. The role of each Cu(II) reagent appears to be distinct and complementary serving to assist catalyst reoxidation and transmetalation through a putative arylcopper intermediate.
Yong Wook Kim; Micah J Niphakis; Gunda I Georg
Related Documents :
23616516 - Intake of small-to-medium-chain saturated fatty acids is associated with peripheral leu...
23705006 - Relevance and diversity of nitrospira populations in biofilters of brackish ras.
6167216 - Plasma amino-acid concentrations during development in the rat.
1118186 - Amino acids of diclidophora merlangi (monogenea).
17926166 - Carboxymethyl xanthan microparticles as a carrier for protein delivery.
9046006 - Effects of mild hypothermia on cerebral blood flow-independent changes in cortical extr...
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2012-10-22
Journal Detail:
Title:  The Journal of organic chemistry     Volume:  77     ISSN:  1520-6904     ISO Abbreviation:  J. Org. Chem.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-02     Completed Date:  2013-03-17     Revised Date:  2013-11-06    
Medline Journal Info:
Nlm Unique ID:  2985193R     Medline TA:  J Org Chem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  9496-503     Citation Subset:  IM    
Department of Chemistry, and the Institute for Therapeutics Discovery and Development, University of Minnesota, 717 Delaware Street SE, Minneapolis, Minnesota 55414, United States.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Amines / chemistry*
Boronic Acids / chemistry*
Copper / chemistry*
Heterocyclic Compounds / chemistry*
Molecular Structure
Palladium / chemistry*
Grant Support
Reg. No./Substance:
0/Amines; 0/Boronic Acids; 0/Heterocyclic Compounds; 7440-05-3/Palladium; 7440-50-8/Copper

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Navigating changing food environments - Transnational perspectives on dietary behaviours and implica...
Next Document:  Genetic differentiation of Ompok bimaculatus (Teleostei: Siluridae) population based on mtDNA cytoch...