Document Detail

Coping and the ineffectiveness of coping influence the outcome of in vitro fertilization through stress responses.
MedLine Citation:
PMID:  1287684     Owner:  NLM     Status:  MEDLINE    
The effect of a coping-ineffectiveness of coping construct and of psychoendocrine stress responses upon the outcome of in vitro fertilization treatment was investigated in 40 women. Women with a high Zung depression score, high active coping, high avoidance, and a high expression of emotion have lower pregnancy rates. The mechanisms for this personality effect are not clear, although the desensitization-stimulation process (FSH, E2 concentrations) seems to be involved. The psychoendocrinological responses to the stress of oocyte retrieval and embryo transfer are important: Women with high anticipatory state anxiety levels and high anticipatory cortisol concentrations have lower pregnancy rates. The influence of prolactin stress concentrations is unclear: Women with high prolactin concentrations seem to have more oocytes but lower fertilization rates.
K Demyttenaere; P Nijs; G Evers-Kiebooms; P R Koninckx
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Psychoneuroendocrinology     Volume:  17     ISSN:  0306-4530     ISO Abbreviation:  Psychoneuroendocrinology     Publication Date:  1992 Nov 
Date Detail:
Created Date:  1993-03-15     Completed Date:  1993-03-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7612148     Medline TA:  Psychoneuroendocrinology     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  655-65     Citation Subset:  IM    
Department of Obstetrics and Gynecology, University Hospital Gasthuisberg, Catholic University, Leuven, Belgium.
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MeSH Terms
Adaptation, Psychological / physiology*
Anxiety / blood,  psychology
Arousal / physiology*
Depression / blood,  psychology
Embryo Transfer / psychology
Fertilization in Vitro*
Follicle Stimulating Hormone / blood
Hydrocortisone / blood
Luteinizing Hormone / blood
Pregnancy / physiology*
Prolactin / blood
Reg. No./Substance:
50-23-7/Hydrocortisone; 9002-62-4/Prolactin; 9002-67-9/Luteinizing Hormone; 9002-68-0/Follicle Stimulating Hormone

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