Document Detail


Co-ordination of cough and swallow in vivo and in silico.
MedLine Citation:
PMID:  22198014     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Coughing and swallowing are airway-protective behaviours. The pharyngeal phase of swallowing prevents aspiration of oral material (saliva, food and liquid) by epiglottal movement, laryngeal adduction and clearing of the mouth and pharynx. Coughing is an aspiration-response behaviour that removes material from the airway. Co-ordination of these behaviours is vital to protect the airway from further aspiration-promoting events, such as a swallowing during the inspiratory phase of coughing. The operational characteristics, primary strategies and peripheral inputs that co-ordinate coughing and swallowing are unknown. This lack of knowledge impedes understanding and treatment of deficits in airway protection, such as the co-occurrence of dystussia and dysphagia common in Parkinson's and Alzheimer's diseases, as well as stroke.
Authors:
Teresa Pitts; Kendall Morris; Bruce Lindsey; Paul Davenport; Ivan Poliacek; Donald Bolser
Related Documents :
19012604 - Hypophagic and dipsogenic effect of the 5-ht1a receptor agonist 8-oh-dpat in broiler ch...
15213024 - Modifications in food-group consumption are related to long-term body-weight changes.
Publication Detail:
Type:  Journal Article; Review     Date:  2011-12-23
Journal Detail:
Title:  Experimental physiology     Volume:  97     ISSN:  1469-445X     ISO Abbreviation:  Exp. Physiol.     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-04-24     Completed Date:  2013-02-01     Revised Date:  2013-06-26    
Medline Journal Info:
Nlm Unique ID:  9002940     Medline TA:  Exp Physiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  469-73     Citation Subset:  IM    
Affiliation:
Department of Physiological Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA. tepitts@ufl.edu
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Cough / physiopathology*
Deglutition / physiology*
Humans
Nerve Net / physiology
Respiration
Respiratory Mechanics / physiology
Grant Support
ID/Acronym/Agency:
R01 HL103415/HL/NHLBI NIH HHS; R01 HL103415-01/HL/NHLBI NIH HHS; R01 HL103415-02/HL/NHLBI NIH HHS; R01 HL103415-03/HL/NHLBI NIH HHS; R33 HL089104-01A1/HL/NHLBI NIH HHS; R33 HL089104-02/HL/NHLBI NIH HHS; R33 HL089104-03/HL/NHLBI NIH HHS; UL1 TR000064/TR/NCATS NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Enhanced insulin secretion and glucose tolerance in rats exhibiting low plasma FFA levels and hypert...
Next Document:  Endurance training decreases the non-linearity in the VO2-power output relationship in humans.