Document Detail

Coordinate regulation of malonyl-CoA decarboxylase, sn-glycerol-3-phosphate acyltransferase, and acetyl-CoA carboxylase by AMP-activated protein kinase in rat tissues in response to exercise.
MedLine Citation:
PMID:  12065578     Owner:  NLM     Status:  MEDLINE    
IN CONCLUSION: MCD, GPAT, and ACC are coordinately regulated by AMPK in liver and adipose tissue in response to exercise, and except for GPAT, also in muscle. The results suggest that AMPK activation plays a major role in regulating lipid metabolism in many cells following exercise. They also suggest that in each of them, it acts to increase fatty acid oxidation and decrease its esterification.
Haejoe Park; Virendar K Kaushik; Scarlet Constant; Marc Prentki; Ewa Przybytkowski; Neil B Ruderman; Asish K Saha
Related Documents :
12016078 - The most effective exercise for strengthening the supraspinatus muscle: evaluation by m...
15030378 - Interstitial glycerol concentrations in human skeletal muscle and adipose tissue during...
20649548 - Redefining the role of mitochondria in exercise: a dynamic remodeling.
16600998 - Higher skeletal muscle alpha2ampk activation and lower energy charge and fat oxidation ...
23749688 - Feasibility and efficacy of a supervised exercise intervention in de-conditioned cancer...
4085478 - Effect of coupling the breathing- and cycling rhythms on oxygen uptake during bicycle e...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.     Date:  2002-06-13
Journal Detail:
Title:  The Journal of biological chemistry     Volume:  277     ISSN:  0021-9258     ISO Abbreviation:  J. Biol. Chem.     Publication Date:  2002 Sep 
Date Detail:
Created Date:  2002-09-02     Completed Date:  2002-10-29     Revised Date:  2014-07-28    
Medline Journal Info:
Nlm Unique ID:  2985121R     Medline TA:  J Biol Chem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  32571-7     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
AMP-Activated Protein Kinases
Acetyl-CoA Carboxylase / metabolism*
Adipose Tissue / enzymology,  metabolism
Carboxy-Lyases / metabolism*
Gene Expression Regulation, Enzymologic
Glycerol-3-Phosphate O-Acyltransferase / metabolism*
Lipid Metabolism
Liver / enzymology
Models, Biological
Multienzyme Complexes / metabolism*
Muscle, Skeletal / enzymology*
Physical Conditioning, Animal*
Precipitin Tests
Protein-Serine-Threonine Kinases / metabolism*
Rats, Sprague-Dawley
Time Factors
Tissue Distribution
Grant Support
Reg. No./Substance:
0/Multienzyme Complexes; EC O-Acyltransferase; EC Protein Kinases; EC Kinases; EC 4.1.1.-/Carboxy-Lyases; EC decarboxylase; EC Carboxylase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Involvement of cell-cell interactions in the rapid stimulation of Cas tyrosine phosphorylation and S...
Next Document:  Genetic analysis of GalR tetramerization in DNA looping during repressosome assembly.