| Conventional mechanical ventilation in acute lung injury and acute respiratory distress syndrome. | |
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MedLine Citation:
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PMID: 17085249 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Acute lung injury and acute respiratory distress syndrome are inflammatory conditions involving a broad spectrum of lung injury from mild respiratory abnormality to severe respiratory derangement. Regardless of cause (direct or indirect lung injury), pulmonary physiology and mechanics are altered, leading to hypoxemic respiratory failure. the use of positive pressure ventilation itself may cause lung injury (ventilator-induced lung injury, or VILI). VILI may amplify preexisting injury, delay lung recovery, and result in adverse outcomes. This article examines the evidence supporting lung-protective ventilation strategies and addresses the methods, outcomes, and potential obstacles to implementation of such approaches. |
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Authors:
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Venktesh R Ramnath; Dean R Hess; B Taylor Thompson |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Clinics in chest medicine Volume: 27 ISSN: 0272-5231 ISO Abbreviation: Clin. Chest Med. Publication Date: 2006 Dec |
Date Detail:
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Created Date: 2006-11-06 Completed Date: 2007-01-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7907612 Medline TA: Clin Chest Med Country: United States |
Other Details:
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Languages: eng Pagination: 601-13; abstract viii Citation Subset: IM |
Affiliation:
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Pulmonary and Critical Care Unit, Department of Medicine, Bulfinch 148, Massachusetts General Hospital, Boston, MA 02114, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Humans Respiration, Artificial / methods* Respiratory Distress Syndrome, Adult / physiopathology, therapy* Tidal Volume / physiology Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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