Document Detail


Convenient and efficient microwave-assisted synthesis of a methyl derivative of the fused indoloquinoline alkaloid cryptosanguinolentine.
MedLine Citation:
PMID:  20657469     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An efficient synthesis of a methyl derivative of the indoloquinoline alkaloid cryptosanguinolentine based on microwave-assisted reactions is described. The microwave-assisted synthesis of an intermediate 4-hydroxy-2-methylquinoline yielded 86% of the desired product and other intermediates prepared yielded high % of products in shorter reaction times, under optimum conditions, as compared to traditional methods.
Authors:
Robert M Gengan; Pitchai Pandian; Chandraprakash Kumarsamy; Palathurai S Mohan
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-04-29
Journal Detail:
Title:  Molecules (Basel, Switzerland)     Volume:  15     ISSN:  1420-3049     ISO Abbreviation:  Molecules     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-07-26     Completed Date:  2010-11-03     Revised Date:  2010-12-15    
Medline Journal Info:
Nlm Unique ID:  100964009     Medline TA:  Molecules     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  3171-8     Citation Subset:  IM    
Affiliation:
Department of Chemistry, Steve Biko Campus, Durban University of Technology, Durban-4001, South Africa. genganrm@dut.ac.za
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MeSH Terms
Descriptor/Qualifier:
Alkaloids / chemical synthesis
Hydroxyquinolines / chemical synthesis*
Indole Alkaloids / chemical synthesis*
Indolequinones / chemical synthesis
Methylation
Microwaves
Quinaldines / chemical synthesis*
Chemical
Reg. No./Substance:
0/Alkaloids; 0/Hydroxyquinolines; 0/Indole Alkaloids; 0/Indolequinones; 0/Quinaldines; 0/cryptosanguinolentine; 91-63-4/2-methylquinoline

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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