Document Detail


A Convenient Access to γ-Lactones from O-Allyl-α-Bromoesters using a One-Pot Ionic-Radical-Ionic Sequence.
MedLine Citation:
PMID:  22556018     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Cognac in the jar! An efficient one-pot sequence for the preparation of γ-lactones is described. Following reduction of α-bromo ester precursors with DIBAL-H and radical cyclization of the resulting O-aluminum acetals, a preparative in-situ Oppenauer-type oxidation of the cyclic O-aluminum acetal using simple aldehydes or ketones gives access to γ-lactones in high yields.
Authors:
Romain Bénéteau; Jacques Lebreton; Fabrice Dénès
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-3
Journal Detail:
Title:  Chemistry, an Asian journal     Volume:  -     ISSN:  1861-471X     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-5-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101294643     Medline TA:  Chem Asian J     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Affiliation:
Université de Nantes, Laboratoire CEISAM, UMR 6230, UFR des Sciences et des Techniques, 2, rue de la Houssinière, BP 92208-44322, Nantes Cedex 3 (France), Fax: (+33) 251-12-54-02.
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