| Convective-controlled double high flux hemodiafiltration: a novel blood purification modality. | |
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MedLine Citation:
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PMID: 15112885 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Convective-controlled double high flux hemodiafiltration (CC-DHF) was set-up using two high flux dialyzers. The convection occurred in the first while the fluid replacement took place in the second dialyzer. The system of CC-DHF basically resembled that of hemodiafiltration. CC-DHF was performed in 9 chronic hemodialysis Thai patients who had been treated with high flux hemodialysis for at least 6 months. When compared with high flux hemodialysis, CC-DHF could provide higher Kt/Vurea (2.4+/-0.4 vs. 2.0+/-0.4, p<0.05) and beta2-microglobulin clearance (106.2+/-15.4 vs. 48.9+/-6.1 ml/min, p<0.01). Following 6-month therapy of CC-HDF, the predialysis beta2-microglobulin levels were reduced by 12.7% while the values of Kt/Vurea were consistently higher than 2.7. The quality of life consistently improved during the 6 months of CC-DHF treatment. There were no differences in clinical and technical complications between CC-DHF and high flux hemodialysis. In conclusion, CC-DHF could provide performance comparable to hemodiafiltration without the need for expensive hemodiafiltration machines. |
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Authors:
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T Pisitkun; S Eiam-Ong; K Tiranathanagul; C Sakunsrijinda; K Manotham; O Hanvivatvong; P Suntaranuson; K Praditpornsilpa; S Chusil; K Tungsanga |
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Publication Detail:
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Type: Comparative Study; Journal Article; Review |
Journal Detail:
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Title: The International journal of artificial organs Volume: 27 ISSN: 0391-3988 ISO Abbreviation: Int J Artif Organs Publication Date: 2004 Mar |
Date Detail:
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Created Date: 2004-04-28 Completed Date: 2004-07-22 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7802649 Medline TA: Int J Artif Organs Country: Italy |
Other Details:
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Languages: eng Pagination: 195-204 Citation Subset: IM |
Affiliation:
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Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Hemodiafiltration
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instrumentation,
methods* Humans Quality of Life Renal Dialysis / instrumentation, methods* Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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