Document Detail

Convective-controlled double high flux hemodiafiltration: a novel blood purification modality.
MedLine Citation:
PMID:  15112885     Owner:  NLM     Status:  MEDLINE    
Convective-controlled double high flux hemodiafiltration (CC-DHF) was set-up using two high flux dialyzers. The convection occurred in the first while the fluid replacement took place in the second dialyzer. The system of CC-DHF basically resembled that of hemodiafiltration. CC-DHF was performed in 9 chronic hemodialysis Thai patients who had been treated with high flux hemodialysis for at least 6 months. When compared with high flux hemodialysis, CC-DHF could provide higher Kt/Vurea (2.4+/-0.4 vs. 2.0+/-0.4, p<0.05) and beta2-microglobulin clearance (106.2+/-15.4 vs. 48.9+/-6.1 ml/min, p<0.01). Following 6-month therapy of CC-HDF, the predialysis beta2-microglobulin levels were reduced by 12.7% while the values of Kt/Vurea were consistently higher than 2.7. The quality of life consistently improved during the 6 months of CC-DHF treatment. There were no differences in clinical and technical complications between CC-DHF and high flux hemodialysis. In conclusion, CC-DHF could provide performance comparable to hemodiafiltration without the need for expensive hemodiafiltration machines.
T Pisitkun; S Eiam-Ong; K Tiranathanagul; C Sakunsrijinda; K Manotham; O Hanvivatvong; P Suntaranuson; K Praditpornsilpa; S Chusil; K Tungsanga
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Publication Detail:
Type:  Comparative Study; Journal Article; Review    
Journal Detail:
Title:  The International journal of artificial organs     Volume:  27     ISSN:  0391-3988     ISO Abbreviation:  Int J Artif Organs     Publication Date:  2004 Mar 
Date Detail:
Created Date:  2004-04-28     Completed Date:  2004-07-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7802649     Medline TA:  Int J Artif Organs     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  195-204     Citation Subset:  IM    
Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
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MeSH Terms
Hemodiafiltration / instrumentation,  methods*
Quality of Life
Renal Dialysis / instrumentation,  methods*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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