Document Detail


Controversies in the physiological basis of the 'anaerobic threshold' and their implications for clinical cardiopulmonary exercise testing.
MedLine Citation:
PMID:  21254986     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This article reviews the notion of the 'anaerobic threshold' in the context of cardiopulmonary exercise testing. Primarily, this is a review of the proposed mechanisms underlying the ventilatory and lactate response to incremental exercise, which is important to the clinical interpretation of an exercise test. Since such tests are often conducted for risk stratification before major surgery, a failure to locate or justify the existence of an anaerobic threshold will have some implications for clinical practice. We also consider alternative endpoints within the exercise response that might be better used to indicate a patient's capacity to cope with the metabolic demands encountered both during and following major surgery.
Authors:
J G Hopker; S A Jobson; J J Pandit
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Anaesthesia     Volume:  66     ISSN:  1365-2044     ISO Abbreviation:  Anaesthesia     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-01-24     Completed Date:  2011-02-24     Revised Date:  2011-11-22    
Medline Journal Info:
Nlm Unique ID:  0370524     Medline TA:  Anaesthesia     Country:  England    
Other Details:
Languages:  eng     Pagination:  111-23     Citation Subset:  AIM; IM    
Copyright Information:
© 2011 The Authors. Anaesthesia © 2011 The Association of Anaesthetists of Great Britain and Ireland.
Affiliation:
Centre for Sports Studies, University of Kent, Chatham Maritime, Chatham, Kent, UK. j.g.hopker@kent.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Anaerobic Threshold / physiology*
Carotid Body / physiology
Exercise / physiology
Exercise Test / methods*
Humans
Hyperventilation / physiopathology
Lactic Acid / metabolism
Terminology as Topic
Chemical
Reg. No./Substance:
50-21-5/Lactic Acid
Comments/Corrections
Comment In:
Anaesthesia. 2011 Nov;66(11):1048-9; author reply 1049-50   [PMID:  22004202 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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