Document Detail


Controversies in neuro-ophthalmology: Steroid therapy for traumatic optic neuropathy.
MedLine Citation:
PMID:  25449942     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
BACKGROUND: There is an increase in the incidence of traumatic optic neuropathy (TON) due to increasing urbanization and rapid spurt in the number of motor vehicles on the road. Despite early presentation and ease of diagnosis the visual outcomes in TON are still limited. There is also significant confusion about the timing, dose and efficacy of steroid treatment in its management.
PURPOSE: To provide a clinical update of the pros and cons of steroid therapy for TON.
DESIGN: The paper is a retrospective review of the currently available literature in the English language indexed in PubMed.
METHODS: A PubMed search was conducted by the authors using the following terms: Traumatic optic neuropathy, megadose, steroids, methylprednisolone. Relevant original articles, review articles, and case reports related to the topic of discussion were evaluated and discussed in the paper.
RESULTS: There is no prospective randomized control trial evaluating the effect of steroids in TON. There are varying reports on the effect of steroid therapy from significant improvement to no difference compared to observation.
CONCLUSION: The decision to give steroids to patients with TON has to be on an individual case to case basis and must involve informed consent from the patient. There are documented advantages and disadvantages of steroid therapy and a prospective, randomized, controlled trial is necessary comparing steroids, surgery and observation before definitive management can be evolved.
Authors:
Rohit Saxena; Digvijay Singh; Vimla Menon
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian journal of ophthalmology     Volume:  62     ISSN:  1998-3689     ISO Abbreviation:  Indian J Ophthalmol     Publication Date:  2014 Oct 
Date Detail:
Created Date:  2014-12-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0405376     Medline TA:  Indian J Ophthalmol     Country:  India    
Other Details:
Languages:  eng     Pagination:  1028-30     Citation Subset:  IM    
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