| Controversies in diagnosis of preterm labour. | |
| | |
MedLine Citation:
|
PMID: 15715597 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Despite scientific advances, efforts to prevent preterm birth can be disappointing. Obstetric care must focus on strategies to improve the outcome of preterm infants. The major goal is to delay preterm birth long enough to allow the transfer of women about to deliver preterm to a facility with a neonatal intensive care unit and to administer corticosteroids to enhance fetal lung maturation. A prerequisite for the success of this strategy is the reliable identification of women who will give birth preterm. Although symptoms of preterm labour strongly suggest preterm birth, contractions-even if combined with cervical effacement and dilation-do not reliably predict preterm birth. The diagnosis of true preterm labour that will eventually lead to preterm birth has been facilitated by the use of transvaginal cervical ultrasonography and by the detection of fetal fibronectin (FFN) in cervicovaginal secretions. The main clinical value of these tests is that preterm birth is very unlikely if the results of both tests are negative. This may help to avoid unnecessary transfer, hospitalisation and treatment of women with false preterm labour. The detection of phosphorylated insulin-like growth factor binding protein-1 in cervicovaginal secretions, or elevated levels of inflammatory markers, like interleukin-6, interleukin-8 and tumour necrosis factor-alpha (TNF-alpha), also predict preterm birth in symptomatic women. These markers, however, are not routinely used to predict preterm birth in women with symptoms of preterm labour. |
| | |
Authors:
|
Harald Leitich |
Related Documents
:
|
7947047 - Feeding the preterm infant. 18754917 - Impaired word stress pattern discrimination in very-low-birthweight infants during the ... 12415047 - Perinatal care at the threshold of viability. 17148007 - Feeding problems in the late preterm infant. 8147327 - Is milk production impaired by dieting during lactation? 19021937 - Retrospective diagnosis of an adverse drug reaction in a breastfed neonate: liquid chro... |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: BJOG : an international journal of obstetrics and gynaecology Volume: 112 Suppl 1 ISSN: 1470-0328 ISO Abbreviation: BJOG Publication Date: 2005 Mar |
Date Detail:
|
Created Date: 2005-02-17 Completed Date: 2005-05-18 Revised Date: 2005-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 100935741 Medline TA: BJOG Country: England |
Other Details:
|
Languages: eng Pagination: 61-3 Citation Subset: AIM; IM |
Affiliation:
|
Department of Obstetrics and Gynecology, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Female Fetus / chemistry Fibronectins / analysis Humans Obstetric Labor, Premature / diagnosis* Pregnancy |
| Chemical | |
Reg. No./Substance:
|
0/Fibronectins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The changing role of progesterone in preterm labour.
Next Document: Management of the neonate at the limits of viability.