Document Detail

Controlling distant metastasis and surgical treatment are crucial for improving clinical outcome in uncommon head and neck malignancies, such as non-squamous cell carcinoma.
MedLine Citation:
PMID:  24940505     Owner:  NLM     Status:  Publisher    
The objective of this study was to elucidate the clinical characteristics of uncommon head and neck malignancies, such as non-squamous cell carcinoma (SCC), in order to improve patient outcomes. A total of 463 head and neck malignancies were retrospectively analyzed, with 43 cases (9.3%) diagnosed as non-SCC. The overall survival rate of patients with adenoid cystic carcinoma was significantly worse compared to that of patients with SCC. The 5-year survival rates were <50% for patients with malignant melanoma, adenocarcinoma, small-cell carcinoma and sarcomas. Distant metastasis to the lung was frequently observed in cases with a poor outcome. Non-SCC malignancies treated without surgery were associated with a worse outcome. Some non-SCC patients had a poor prognosis and distant metastasis was associated with an unsatisfactory outcome. Timely treatment and control of distant metastasis are essential and surgical treatment should be prioritized in non-SCC cases to improve patient outcomes.
Masashi Shiiba; Motoharu Unozawa; Morihiro Higo; Yukinao Kouzu; Atsushi Kasamatsu; Yosuke Sakamoto; Katsunori Ogawara; Katsuhiro Uzawa; Yuichi Takiguchi; Hideki Tanzawa
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-5-08
Journal Detail:
Title:  Molecular and clinical oncology     Volume:  2     ISSN:  2049-9450     ISO Abbreviation:  Mol Clin Oncol     Publication Date:  2014 Jul 
Date Detail:
Created Date:  2014-6-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101613422     Medline TA:  Mol Clin Oncol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  609-617     Citation Subset:  -    
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