| Controlled trials comparing reteplase with alteplase and streptokinase in patients with acute myocardial infarction. | |
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MedLine Citation:
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PMID: 8888101 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Although the ability of a thrombolytic agent to lyse a clot has been recognized for over 50 years, it was not until recently that this form of therapy was used to treat acute myocardial infarction. The need for rapid diagnosis and timely treatment to provide optimum outcomes and prognosis is now well established. Numerous clinical trials continue to examine alternative therapeutic regimens as well as the efficacy and safety of new agents to improve short- and long-term outcomes further. Reteplase is a new recombinant tissue-type plasminogen activator with potential advantages over currently available agents. |
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Authors:
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E A Amsterdam |
Publication Detail:
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Type: Comparative Study; Journal Article; Review |
Journal Detail:
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Title: Pharmacotherapy Volume: 16 ISSN: 0277-0008 ISO Abbreviation: Pharmacotherapy Publication Date: 1996 Sep-Oct |
Date Detail:
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Created Date: 1997-01-31 Completed Date: 1997-01-31 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8111305 Medline TA: Pharmacotherapy Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 137S-140S Citation Subset: IM |
Affiliation:
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Department of Medicine, School of Medicine, University of California, Davis, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Controlled Clinical Trials as Topic Fibrinolytic Agents / therapeutic use* Humans Myocardial Infarction / drug therapy* Plasminogen Activators / therapeutic use* Recombinant Proteins / therapeutic use Streptokinase / therapeutic use* Tissue Plasminogen Activator / therapeutic use* |
| Chemical | |
Reg. No./Substance:
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0/Fibrinolytic Agents; 0/Recombinant Proteins; 133652-38-7/reteplase; EC 3.4.-/Streptokinase; EC 3.4.21.-/Plasminogen Activators; EC 3.4.21.68/Tissue Plasminogen Activator |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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