Document Detail

Controlled trials comparing reteplase with alteplase and streptokinase in patients with acute myocardial infarction.
MedLine Citation:
PMID:  8888101     Owner:  NLM     Status:  MEDLINE    
Although the ability of a thrombolytic agent to lyse a clot has been recognized for over 50 years, it was not until recently that this form of therapy was used to treat acute myocardial infarction. The need for rapid diagnosis and timely treatment to provide optimum outcomes and prognosis is now well established. Numerous clinical trials continue to examine alternative therapeutic regimens as well as the efficacy and safety of new agents to improve short- and long-term outcomes further. Reteplase is a new recombinant tissue-type plasminogen activator with potential advantages over currently available agents.
E A Amsterdam
Publication Detail:
Type:  Comparative Study; Journal Article; Review    
Journal Detail:
Title:  Pharmacotherapy     Volume:  16     ISSN:  0277-0008     ISO Abbreviation:  Pharmacotherapy     Publication Date:    1996 Sep-Oct
Date Detail:
Created Date:  1997-01-31     Completed Date:  1997-01-31     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8111305     Medline TA:  Pharmacotherapy     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  137S-140S     Citation Subset:  IM    
Department of Medicine, School of Medicine, University of California, Davis, USA.
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MeSH Terms
Acute Disease
Controlled Clinical Trials as Topic
Fibrinolytic Agents / therapeutic use*
Myocardial Infarction / drug therapy*
Plasminogen Activators / therapeutic use*
Recombinant Proteins / therapeutic use
Streptokinase / therapeutic use*
Tissue Plasminogen Activator / therapeutic use*
Reg. No./Substance:
0/Fibrinolytic Agents; 0/Recombinant Proteins; 133652-38-7/reteplase; EC 3.4.-/Streptokinase; EC 3.4.21.-/Plasminogen Activators; EC Plasminogen Activator

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