Document Detail

Controlled trials of Antabuse in alcoholism: the importance of supervision and adequate dosage.
MedLine Citation:
PMID:  1471553     Owner:  NLM     Status:  MEDLINE    
Methods of using Antabuse have changed since its introduction over 40 years ago. Several randomised controlled trials have shown that Antabuse can make a statistically and clinically significant contribution to treatment outcome in alcoholism but only if its administration is carefully supervised. The recent literature is reviewed. Adequate dosage is important and the recommended maximum in some countries is often insufficient. Both prescribers and supervisors of Antabuse need to be aware of the ways in which some patients try to evade medication.
C Brewer
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Acta psychiatrica Scandinavica. Supplementum     Volume:  369     ISSN:  0065-1591     ISO Abbreviation:  Acta Psychiatr Scand Suppl     Publication Date:  1992  
Date Detail:
Created Date:  1993-01-25     Completed Date:  1993-01-25     Revised Date:  2008-02-15    
Medline Journal Info:
Nlm Unique ID:  0370365     Medline TA:  Acta Psychiatr Scand Suppl     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  51-8     Citation Subset:  IM    
Stapleford Centre, Belgravia, London, United Kingdom.
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MeSH Terms
Alcoholism / drug therapy*
Disulfiram / administration & dosage,  therapeutic use*
Outcome Assessment (Health Care)
Patient Compliance*
Reg. No./Substance:

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