| Controlled trials of Antabuse in alcoholism: the importance of supervision and adequate dosage. | |
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MedLine Citation:
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PMID: 1471553 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Methods of using Antabuse have changed since its introduction over 40 years ago. Several randomised controlled trials have shown that Antabuse can make a statistically and clinically significant contribution to treatment outcome in alcoholism but only if its administration is carefully supervised. The recent literature is reviewed. Adequate dosage is important and the recommended maximum in some countries is often insufficient. Both prescribers and supervisors of Antabuse need to be aware of the ways in which some patients try to evade medication. |
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Authors:
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C Brewer |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Acta psychiatrica Scandinavica. Supplementum Volume: 369 ISSN: 0065-1591 ISO Abbreviation: Acta Psychiatr Scand Suppl Publication Date: 1992 |
Date Detail:
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Created Date: 1993-01-25 Completed Date: 1993-01-25 Revised Date: 2008-02-15 |
Medline Journal Info:
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Nlm Unique ID: 0370365 Medline TA: Acta Psychiatr Scand Suppl Country: DENMARK |
Other Details:
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Languages: eng Pagination: 51-8 Citation Subset: IM |
Affiliation:
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Stapleford Centre, Belgravia, London, United Kingdom. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Alcoholism / drug therapy* Disulfiram / administration & dosage, therapeutic use* Female Humans Male Outcome Assessment (Health Care) Patient Compliance* |
| Chemical | |
Reg. No./Substance:
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97-77-8/Disulfiram |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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